Chapter 48: Neurobiology of Psychotic Illnesses

Chapter 48: Neurobiology of Psychotic Illnesses

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE
1. Schizophrenia is characterized by
a. generalized anxiety.
b. depression.
c. disorganized thinking.
d. eating disorders.
ANS: C
Schizophrenia is now correctly understood as a split or separation among normally well-synchronized brain functions. This loss of
synchronized brain functioning leads to thoughts, behaviors, and feelings that are disordered, disorganized, and disconnected from
reality. Generalized anxiety and eating disorders are not associated with schizophrenia. Schizophrenia is not characterized by
depression.
REF: Pg. 975
2. The usual age of onset for schizophrenia in men is
a. before puberty.
b. 15 to 25 years.
c. 40 to 65 years.
d. after 65 years.
ANS: B
The most common age of onset and diagnosis is between 15 and 25 years for men. Women are typically diagnosed between 25 and
35 years. Most persons first diagnosed with schizophrenia are between the ages of 15 and 54 years. The usual age of onset of
schizophrenia occurs before the age of 25.
REF: Pg. 975
3. Which manifestation is characteristic of the “positive” symptoms of schizophrenia?
a. Social withdrawal
b. Flat affect
c. Lack of speech
d. Hallucinations
ANS: D
Positive symptoms include the psychotic dimension, or distortions in thought content (delusions) and perception (hallucinations), as
well as the disorganization dimension, or disorganization in speech and behavior. Asociality is considered a negative symptom. Flat
affect is considered to be a cognitive symptom. Lack of speech is not considered to be a positive symptom of schizophrenia.
REF: Pg. 978
4. It is true that the “negative” symptoms of schizophrenia
a. are more easily managed than the positive symptoms.
b. are thought to be mediated by D1 receptors in the brain.
c. include rambling speech and delusional thoughts.
d. are due to a deficiency of brain dopamine.
ANS: B
Negative symptoms of schizophrenia are thought to be associated with dopamine D1 receptor activity in the brain. Negative
symptoms can be more difficult to recognize than positive symptoms. Rambling speech and delusional thoughts are positive
symptoms. The positive symptoms of schizophrenia are thought to result from excessive dopamine D2 receptor activity in the brain.