Chapter 08: Gene Therapy and Pharmacogenomics

Chapter 08: Gene Therapy and Pharmacogenomics

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

1. The nurse is reviewing the applications of gene therapy. Which drug is manufactured as a result of indirect gene therapy?

a.	Vitamin K
b.	Warfarin
c.	Human insulin
d.	Heparin

 

 

ANS:  C

A recombinant form of human insulin is one of the most widespread uses of indirect gene therapy. Other examples include hormones, vaccines, antitoxins, and monoclonal antibodies. The other options listed are not examples of drugs manufactured by indirect gene therapy.

 

DIF:    COGNITIVE LEVEL: Remembering (Knowledge)           REF:   p. 98

TOP:   NURSING PROCESS: General

MSC:  NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

 

2. The nurse is discussing gene therapy in a continuing education class. Which is the best definition of eugenics?

a.	The use of gene therapy to prevent disease
b.	The development of new drugs based on gene therapy
c.	Intentional selection, before birth, of genotypes that are considered more desirable than others
d.	The determination of genetic factors that influence a person’s response to medications

 

 

ANS:  C

Eugenics is the intentional selection of genotypes, before birth, that are considered more desirable than others, and it is a major ethical issue concerning gene therapy. The other options do not describe eugenics.

 

DIF:    COGNITIVE LEVEL: Understanding (Comprehension)    REF:   p. 99

TOP:   NURSING PROCESS: General

MSC:  NCLEX: Physiological Integrity: Pharmacological Therapies

 

3. The nurse is explaining the Human Genome Project to colleagues. Which of these is the main purpose of the Human Genome Project?

a.	The study of genetic diseases.
b.	The study of genetic traits in humans.
c.	The discovery new genetic diseases.
d.	To describe the entire genome of a human being.

 

 

ANS:  D

The Human Genome Project was undertaken to describe in detail the entire genome of a human being. The other options do not describe the Human Genome Project.

 

DIF:    COGNITIVE LEVEL: Remembering (Knowledge)           REF:   p. 98

TOP:   NURSING PROCESS: General

MSC:  NCLEX: Physiological Integrity: Physiological Adaptation

 

4. A patient has just been told that she has the genetic markers for a severe type of breast cancer. After the patient meets with the physician, the patient’s daughter asks the nurse, “What did the doctor tell my mother? She seems upset.” What is the nurse’s best response?

a.	“I’m sorry, but I’m not allowed to discuss that.”
b.	“The physician will discuss this with you.”
c.	“It seems that your mother has the genetic markers for a type of breast cancer.”
d.	“This is information that your mother will need to discuss with you.”

 

 

ANS:  D

Maintaining privacy and confidentiality is of utmost importance during genetic testing and counseling. The patient (not the nurse or the physician) is the one who decides whether to include or exclude any family members from the discussion and from knowledge of the results of genetic testing. Telling the patient’s daughter that you are “not allowed” to discuss the matter would cause more anxiety. Telling the daughter about the genetic markers would be a violation of the patient’s privacy.

 

DIF:    COGNITIVE LEVEL: Applying (Application)                  REF:   pp. 100-101

TOP:   NURSING PROCESS: Implementation

MSC:   NCLEX: Physiological Integrity: Physiological Adaptation