Chapter 5: Pharmacodynamics

Chapter 5: Pharmacodynamics

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

1. A nurse is trying to ensure a nursing student’s understanding regarding drug interactions with receptor binding. Which statement made by the nursing student indicates a need for further teaching?

a.	Drugs can bind to receptors and cause activation.
b.	Drugs can bind to receptors and block receptor activation by other agents.
c.	Drugs can bind receptor components and enhance receptor activation.
d.	Drugs bind to receptors and thereby alter a cell’s function.

 

 

ANS:   D

Drugs bind to receptors but do NOT alter a cell’s function.

Drugs do bind to receptors and cause activation.

Drugs can bind to receptors and block receptor activation by other agents.

Drugs can also bind receptor components and enhance receptor activation.

 

DIF:    Cognitive Level: Comprehension      REF:    pp. 50-51

TOP:    Nursing Process: Evaluation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

2. Two nurses are discussing theories of drug-receptor interaction. One of the nurses states that which of the following statements is(are) true regarding the affinity of a drug and its receptor? (Select all that apply.)

a.	Affinity and intrinsic activity are dependent properties.
b.	Affinity refers to the strength of the attraction between a drug and its receptor.
c.	Drugs with high affinity are strongly attracted to their receptors.
d.	Drugs with low affinity are strongly attracted to their receptors.
e.	The affinity of a drug for its receptors is reflected in its potency.

 

 

ANS:   B, C, E

Affinity does refer to the strength of the attraction between a drug and its receptor, drugs with high affinity are strongly attracted to their receptors, and the affinity of a drug for its receptors is reflected in its potency.

Affinity and intrinsic activity are independent properties.

Drugs with low affinity are weakly attracted to their receptors.

 

DIF:    Cognitive Level: Comprehension      REF:    pp. 51-52

TOP:    Nursing Process: Diagnosis

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

3. Education on pharmacology is taking place on the nursing unit. The discussion involves the receptor sensitivity of a medication. The presenter asks the nurses to provide an example of desensitization. Which of the following responses would be an example of desensitization?

a.	The synthesis of more receptors
b.	Continuous exposure to antagonists
c.	Continual exposure to an agonist
d.	Antacids used to reduce gastric acid

 

 

ANS:   C

Continual exposure to an agonist would cause the cell to become less responsive or desensitized.

The synthesis of more receptors would create a hypersensitivity reaction.

Continuous exposure to antagonists would also contribute to hypersensitivity.

Antacids used to reduce gastric acid are an example of receptorless drugs.

 

DIF:    Cognitive Level: Application             REF:    p. 53

TOP:    Nursing Process: Implementation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies