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Chapter 39: Osteoporosis Treatment

Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew

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Chapter 39: Osteoporosis Treatment

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. A 55-year-old woman who experienced menopause at age 50 years undergoes central dual-energy x-ray absorptiometry and has a T-score greater than 2.5. The patient weighs 130 lb and has a body mass index of 22. She sits at a computer all day at work. The primary care nurse practitioner (NP) caring for this patient should:
a. prescribe a bisphosphonate.
b. prescribe hormone replacement therapy.
c. counsel the patient about diet and exercise.
d. prescribe a selective estrogen receptor modulator.

 

 

ANS:  C

The NP should counsel the patient about diet and exercise. Women who are at least 5 years postmenopausal or who have several risk factors should have bone density testing. Osteoporosis is defined as a T-score of less than 2.5, and treatment is indicated for women with T-scores that are 2 or more standard deviations below the normal premenopausal level. It is not necessary to initiate treatment at this time.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   435

 

  1. A 50-year-old white woman who is experiencing menopause asks the primary care NP what she can do to prevent osteoporosis. She has a negative family history and no risk factors. The NP should counsel her to:
a. consider bisphosphonate therapy in 5 years.
b. undergo bone density testing every 2 years.
c. avoid high-impact sports that can lead to fractures.
d. take supplemental calcium and vitamin D every day.

 

 

ANS:  D

Postmenopausal women should consume 1200 mg of calcium and at least 1000 U of vitamin D each day. Bisphosphonate therapy should be considered for persons with known risk factors. Bone density testing is indicated for women with risk factors and then routinely after age 65. Patients should be encouraged to engage in high-impact sports if possible to improve bone density.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   433

 

  1. A 60-year-old woman has a central dual-energy x-ray absorptiometry with a T-score of 1.9. A health history reveals no risk factors for osteoporosis. The primary care NP should:
a. prescribe alendronate sodium (Fosamax).
b. counsel her to increase her physical activity.
c. prescribe calcitonin (Miacalcin nasal spray).
d. prescribe supplemental calcium and vitamin D.

 

 

ANS:  A

This woman’s T-score is less than 2.5 and indicates osteoporosis. She should begin treatment with a bisphosphonate. Increasing physical activity and taking supplemental calcium and vitamin D are indicated as well but only as part of a medication regimen. Calcitonin is not a first-line medication.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   433

 

  1. A 70-year-old patient who has a high fracture risk has been taking alendronate (Fosamax) and calcium for 6 months. The primary care NP orders a urine NTx level, which is 42. The NP should discontinue the alendronate and prescribe:
a. raloxifene (Evista).
b. teriparatide (Forteo).
c. calcitonin (Miacalcin nasal spray).
d. ibandronate sodium (Boniva).

 

 

ANS:  B

Teriparatide is used in patients with a high fracture risk or in whom bisphosphonate therapy has failed. Raloxifene and ibandronate are second-line treatments for patients with usual fracture risks. Calcitonin is a last-line treatment.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   436

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