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Chapter 60: Cephalosporins

Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew

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Chapter 60: Cephalosporins

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. An adult patient has cellulitis. The patient is a single parent with health insurance who works and is attending classes at a local university. To treat this infection, the primary care nurse practitioner (NP) should prescribe:
a. cefdinir (Omnicef).
b. cephalexin (Keflex).
c. cefadroxil (Duricef).
d. ceftriaxone (Rocephin).

 

 

ANS:  C

First-generation cephalosporins, such as cephalexin and cefadroxil, are used for skin and soft tissue infections. Cefadroxil is preferred in this case because it can be given twice daily instead of four times daily, and this patient will be more likely to comply with the drug regimen. Cefdinir and ceftriaxone are both third-generation cephalosporins.

 

DIF:    Cognitive Level: Understanding (Comprehension)             REF:   678

 

  1. A primary care NP sees a patient who has dysuria, fever, and urinary frequency. The NP orders a urine dipstick, which is positive for nitrates and leukocyte esterase, and sends the urine to the laboratory for a culture. The patient is allergic to sulfa drugs. The NP should:
a. order cefaclor (Ceclor).
b. prescribe cefixime (Suprax).
c. administer intramuscular ceftriaxone (Rocephin).
d. wait for culture results before ordering an antibiotic.

 

 

ANS:  B

Cephalosporins are useful for empirical treatment of many of the most common infections seen in primary care. Cefixime is a third-generation cephalosporin, which has greater activity against Escherichia coli and excellent penetration into body fluids, making it a good choice for empirical treatment of urinary tract infection.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   678

 

  1. A patient is taking cefadroxil (Duricef) and comes to the clinic complaining of loose stools for several days. The primary care NP notes normal vital signs; warm, pink skin with elastic turgor; and moist mucous membranes. The NP should:
a. order tests for Clostridium difficile–associated disease (CDAD).
b. discontinue the cefadroxil.
c. reassure the patient that loose stools are common with antibiotics.
d. recommend consuming lactobacillus-containing foods to minimize diarrhea.

 

 

ANS:  A

The U.S. Food and Drug Administration (FDA) advises that CDAD be considered in all patients who present with diarrhea after antibiotic use. This patient’s symptoms are mild, so discontinuation of the drug is not warranted unless CDAD is present.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   680 – 681

 

  1. A primary care NP provides teaching to a patient who will begin taking cefadroxil (Duricef). Which statement by the patient indicates a need for further teaching?
a. “I should report any rash that occurs.”
b. “I will take this medication twice daily.”
c. “I should take this medication with food.”
d. “Gastrointestinal (GI) symptoms are common but not worrisome.”

 

 

ANS:  D

The FDA advises that CDAD be considered in all patients who present with diarrhea after antibiotic use. Patients should be taught to report all GI symptoms.

 

DIF:     Cognitive Level: Applying (Application)                       REF:    680 – 681

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