Pharmacotherapeutics for Advanced Practice 3rd Edition by Virginia Poole Arcangelo, Andrew M. Peterson
Pharmacotherapeutics for Advanced Practice 3rd Edition by Virginia Poole Arcangelo, Andrew M. Peterson
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Chapter 4. Principles of Pharmacotherapy in Children
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| A. | All children be provided equal access to drug research trials |
| B. | Children to be included in the planning phase of new drug development |
| C. | That pediatric drug trials guarantee children of multiple ethnic groups are included |
| D. | All applications for new active ingredients, new indications, new dosage forms, or new routes of administration require pediatric studies |
ANS: D PTS: 1
| A. | Includes a pediatric exclusivity rule which extends the patent on drugs studied in children |
| B. | Establishes a committee that writes guidelines for pediatric prescribing |
| C. | Provides funding for new drug development aimed at children |
| D. | Encourages manufacturers specifically to develop pediatric formulations |
ANS: B PTS: 1
| A. | None, Phase I enzymes are stable throughout childhood. |
| B. | Children should always be prescribed lower than adult doses per weight due to low enzyme activity until puberty. |
| C. | Children should always be prescribed higher than adult doses per weight due to high enzyme activity. |
| D. | Prescribing dosages will vary based on the developmental activity of each enzyme, at times requiring lower than adult doses and other times higher than adult doses based on the age of the child. |
ANS: D PTS: 1
| A. | Lower doses of renally excreted drugs may be prescribed to infants younger than age 6 months. |
| B. | Higher doses of water soluble drugs may need to be prescribed due to increased renal excretion. |
| C. | Renal excretion rates have no impact on prescribing. |
| D. | Parents need to be instructed on whether drugs are renally excreted or not. |
ANS: A PTS: 1
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