Chapter 5: Cell proliferation, apoptosis, repair and regeneration

Chapter 5: Cell proliferation, apoptosis, repair and regeneration

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. In the death receptor pathway, activation of tumor necrosis factor receptors causes the receptors to trimerize and complex an adapter protein, thereby leading to activation of

1. mitochondrial pathways
2. caspase-8
3. pro-apoptotic factor Bcl-2
4. a p53 protein
5. DNA transcription factors

Answer b: caspase-8

1. The activation of primitive stem cells so as to replace a damaged tissue is called

1. healing
2. repair
3. restoration
4. regeneration
5. rejuvenation

Answer d: regeneration

1. Defective apoptosis may contribute to the development of

1. cancer
2. Alzheimer’s disease
3. myocardial infarction
4. aplastic anemia
5. stroke

Answer a: cancer

1. The activation of caspase-3 leads to

1. activation of transcription factors
2. inhibition of transcription factors
3. activation of the anti-apoptotic pathway
4. fragmentation of genomic DNA
5. stabilization of cell membranes

Answer d: fragmentation of genomic DNA

1. Bortemozib causes accumulation of an apoptotic-promoter protein by inhibiting

1. mitochondrial DNA
2. suvivin
3. matrix metalolproteinases
4. pro-apoptotic Bcl-2
5. the proteasome

Answer e: the proteasome