Chapter 4: How drugs act: cellular aspects—excitation, contraction and secretion

Chapter 4: How drugs act: cellular aspects—excitation, contraction and secretion

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. L(long-lasting)-type calcium channels are correctly described as having

1. low activation threshold and slow inactivation
2. high activation threshold and slow inactivation
3. low activation threshold and fast inactivation
4. high activation threshold and fast inactivation
5. none of the above as correct

Answer b: high activation threshold and slow inactivation

1. The extrusion of calcium from the cell cytoplasm primarily depends on

1. ligand-gated calcium channels
2. voltage-gated calcium channels
3. the sodium-calcium exchange transporter
4. the ATP-driven calcium pump
5. nuclear sequestration

Answer d: the ATP-driven calcium pump

1. The mechanism by which monamine neurotransmitters are released from nerve terminals is

1. calcium-mediated exocytosis
2. carrier-mediated release
3. ATP-dependent active transport
4. diffusion through aqueous pores
5. diffusion through membrane lipid

Answer a: calcium-mediated exocytosis

1. Batrachotoxin binds sodium channels and thereby

1. opens channels
2. prevents channel opening
3. prevents channel inactivation
4. closes channels
5. causes channels to remain closed

Answer c: prevents channel inactivation