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Chapter 41: Analgesic drugs

Rang & Dale's Pharmacology by Humphrey P. Rang

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Chapter 41: Analgesic drugs

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. Opioids activate descending pathways that inhibit pain transmission by acting on neurons in the

 

  1. dorsal horn
  2. thalamus
  3. periaqueductal grey matter
  4. nucleus raphe magnus
  5. locus coeruleus

 

Answer c: periaqueductal grey matter

 

  1. The vanilloid receptor activated by capsaicin is a

 

  1. ligand-gated cation channel
  2. ligand-gated chloride ion channel
  3. ATP-sensitive potassium channel
  4. G-protein-coupled receptor
  5. protein kinase receptor

 

Answer a: ligand-gated cation channel

 

  1. The analgesic effect of morphine is mostly due to activation of

 

  1. delta opioid receptors
  2. kappa opioid receptors
  3. mu opioid receptors
  4. sigma opioid receptors
  5. tau receptors

 

Answer c: mu opioid receptors

 

  1. Stimulation of opioid receptors leads to

 

  1. increased guanylate cyclase activity
  2. decreased guanylate cyclase activity
  3. increased adenylate cyclase activity
  4. decreased adenylate cyclase activity
  5. closing of potassium channels

 

Answer d: decreased adenylate cyclase activity

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