Chapter 44: Antiepileptic drugs

Chapter 44: Antiepileptic drugs

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. Gabapentin is believed to exert its antiepileptic effect by

1. increasing the synthesis of  g-aminobutyric acid (GABA)
2. increasing the release of g-aminobutyric acid (GABA)
3. activating g-aminobutyric acid (GABA)-gated chloride ion channels
4. blocking g-aminobutyric acid (GABA)-gated chloride ion channels
5. inhibiting the release of several neurotransmitters

Answer e: inhibiting the release of several neurotransmitters

1. The efficacy of ethosuximide in the treatment of absence seizures is based on its ability to

1. block voltage-dependent sodium channels
2. activate voltage-dependent sodium channels
3. block T (transient)-type calcium channels
4. activate T (transient)-type calcium channels
5. activated g-aminobutyric acid (GABA)-gated chloride ion channels

Answer c: block T (transient)-type calcium channels

1. Which antiepileptic agent inhibits g-aminobutyric acid (GABA) transaminase and thereby increases the brain content of GABA?

1. vigabatrin
2. carbamazepine
3. tiagabine
4. lamotrigine
5. topiramate

Answer a: vigabatrin

1. Carbamazepine is used in treating all of the following conditions except

1. bipolar disorder
2. neuropathic pain
3. absence seizures
4. partial seizures
5. generalized tonic-clonic seizures

Answer c: absence seizures