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Chapter 32: Drug Therapy for Female Reproductive Issues

Understanding Pharmacology Essentials For Medication Safety By M. Linda Workman

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Chapter 32: Drug Therapy for Female Reproductive Issues

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

BASIC CONCEPTS

 

  1. What is the most serious adverse effect of hormone replacement therapy for menopause?
a. Pregnancy
b. Blood clots
c. Miscarriage
d. Decreased mental concentration

 

 

ANS:  B

Hormone replacement therapy for perimenopausal symptoms uses different types of estrogens and sometimes progesterone. Exogenous use of these drugs increases the risk for forming blood clots where they are not needed, leading to the potential venous thromboembolism complications of deep vein thrombosis, strokes, and heart attacks.

 

DIF:    Cognitive Level: Remembering        REF:   p. 498

 

  1. Which hormone levels in the blood are reduced as a result of taking hormone replacement therapy for menopause?
a. Estrogen and progesterone
b. Estrogen and follicle stimulating hormone
c. Gonadotrophin releasing hormone and progesterone
d. Follicle stimulating hormone and gonadotrophin releasing hormone

 

 

ANS:  D

The blood levels of estrogen are increased during hormone replacement therapy, which reduces the release of gonadotrophin releasing hormone from the brain. With low levels of gonadotrophin releasing hormone, the anterior pituitary gland greatly reduces secretion of follicle stimulating hormone.

 

DIF:    Cognitive Level: Remembering        REF:   p. 494

 

  1. Which side effects are most common among women taking hormone replacement therapy for menopause?
a. Breast tenderness and fluid retention
b. Increased vaginal dryness and constipation
c. Nausea, vomiting, and diarrhea
d. Skin itching and dark-colored urine

 

 

ANS:  A

The most common side effects of hormone replacement therapy for perimenopausal symptoms are breast tenderness, breakthrough bleeding, fluid retention, weight gain, and acne. Vaginal dryness is reduced, not increased. Skin itching is reduced, not increased. Dark urine would be a symptom of the adverse effect of liver toxicity. These drugs are not commonly a cause of any gastrointestinal problems.

 

DIF:    Cognitive Level: Remembering        REF:   p. 496

 

  1. Which brand name oral contraceptive contains drospirenone?
a. Camila
b. Ovral
c. Yasmin
d. Zovia

 

 

ANS:  C

The brand of oral contraceptive known as Yasmin is a combination of drospirenone and ethinyl estradiol.

 

DIF:    Cognitive Level: Remembering        REF:   p. 497, Table 32-1

 

  1. Which female hormone supports pregnancy by directly maintaining the thickened uterine lining?
a. Estrogen
b. Progesterone
c. Luteinizing hormone
d. Follicle stimulating hormone

 

 

ANS:  B

Estrogen increases the thickness of the uterine lining and then progesterone maintains this lining making the uterus ready for implantation. Luteinizing hormone stimulates ovulation and follicle stimulating hormone causes the ovary to produce estrogen.

 

DIF:    Cognitive Level: Remembering        REF:   p. 493

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