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Chapter 12: Basic Principles of Neuropharmacology

Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne

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Chapter 12: Basic Principles of Neuropharmacology

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

  1. A nurse is trying to ensure a student nurse’s understanding of drug interactions with receptor binding. Which statement made by the student indicates a need for further teaching?
a. Drugs can bind to receptors and cause activation.
b. Drugs can bind to receptors and block receptor activation by other agents.
c. Drugs can bind receptor components and enhance receptor activation by the natural transmitter at the site.
d. Drugs bind to receptors and thereby alter a cell’s function.

 

 

ANS:   D

Drugs do not alter cellular function; this statement indicates a need for further teaching.

Drugs can bind to receptors and activate them; no further teaching is indicated.

Drugs may block the receptor site; no further teaching is indicated.

Drugs can enhance transmitter effects; no further teaching is needed.

 

DIF:    Cognitive Level: Comprehension      REF:    p. 101

TOP:    Nursing Process: Diagnosis

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

  1. A nurse administers drug A to a patient. The nurse understands that the more types of receptors there are for the drug to work with, the greater the chance of producing which effect in the patient?
a. Toxic levels
b. Subtherapeutic levels
c. Selective drug effects
d. Minimal drug effects

 

 

ANS:   C

Selective drug effects are elicited when more types of receptors are available for the drug to work with.

Toxic levels would more likely be produced by too much of a drug, not by the greater number of receptors available for the drug to work with.

Subtherapeutic levels are related to the presence of a smaller amount of the drug or to fewer doses of the drug rather than more types of receptors available for the drug to work with.

Minimal drug effects would be below the minimal concentration and therefore the same as subtherapeutic effects.

 

DIF:    Cognitive Level: Analysis                  REF:    p. 103

TOP:    Nursing Process: Evaluation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

  1. A nurse is teaching a class on neuropharmacology to a group of nurses. The nurse asks the participants which classes of drugs act by reducing axonal conduction. Which response by one of the participants best demonstrates an appropriate understanding of this concept?
a. Antihypertensives
b. Antipsychotics
c. Local anesthetics
d. Antidepressants

 

 

ANS:   C

Local anesthetics are the only drugs shown to work by reducing axonal conduction.

Antihypertensives, antipsychotics, and antidepressants do not act by reducing axonal conduction.

 

DIF:    Cognitive Level: Analysis                  REF:    p. 101

TOP:    Nursing Process: Evaluation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

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