Chapter 46: Antineoplastic Drugs Part 2: Cell Cycle–Nonspecific Drugs and Miscellaneous Drugs

Chapter 46: Antineoplastic Drugs Part 2: Cell Cycle–Nonspecific Drugs and Miscellaneous Drugs

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

1. A patient is receiving doxorubicin (Adriamycin) as part of treatment for ovarian cancer. Which nursing diagnosis is related to this antineoplastic drug?

a.	Decreased cardiac output related to the adverse effect of cardiotoxicity
b.	Ineffective breathing pattern related to the adverse effect of pulmonary toxicity
c.	Risk for injury related to the effects of neurotoxicity (ataxia, numbness of hands and feet)
d.	Impaired urinary elimination pattern related to hyperuricemia

 

 

ANS:  A

Decreased cardiac output related to the adverse effect of cardiotoxicity is a nursing diagnosis related to doxorubicin because adverse effects of doxorubicin include liver and cardiovascular toxicities. The other options are incorrect.

 

DIF:    COGNITIVE LEVEL: Applying (Application)                  REF:   p. 742

TOP:   NURSING PROCESS: Nursing Diagnosis

MSC:  NCLEX: Physiological Integrity: Physiological Adaptation

 

2. When giving cisplatin (Platinol-AQ), the nurse is aware that the major dose-limiting effect of this drug is which condition?

a.	Alopecia
b.	Kidney damage
c.	Cardiotoxicity
d.	Stomatitis

 

 

ANS:  B

Cisplatin may cause nephrotoxicity, and the patient’s renal function must be monitored closely while on this drug. Ensuring hydration will help to prevent nephrotoxicity.

 

DIF:    COGNITIVE LEVEL: Understanding (Comprehension)    REF:   p. 735

TOP:   NURSING PROCESS: Implementation

MSC:  NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

 

3. The nurse is teaching a class about the various chemotherapy drugs. Which of these statements explains why alkylating drugs are also called “cell cycle–nonspecific drugs”?

a.	They are cytotoxic during a specific cell cycle.
b.	They are cytotoxic in any phase of the cell cycle.
c.	They are effective against several types of neoplasms.
d.	They are more highly differentiated than cell cycle–specific drugs.

 

 

ANS:  B

Cell cycle–nonspecific drugs kill cancer cells during any phase of the growth cycle, whereas cell cycle–specific drugs kill cancer cells during specific phases of the cell growth cycle. The other options are incorrect.

 

DIF:    COGNITIVE LEVEL: Understanding (Comprehension)    REF:   p. 734

TOP:   NURSING PROCESS: Evaluation

MSC:  NCLEX: Physiological Integrity: Reduction of Risk Potential

 

4. What is the nurse’s priority action if extravasation of an antineoplastic drug occurs during intravenous (IV) administration?

a.	Reduce the infusion rate.
b.	Discontinue the IV, and apply warm compresses.
c.	Stop the infusion immediately, but leave the IV catheter in place.
d.	Change the infusion to normal saline, and inject the area with hydrocortisone.

 

 

ANS:  C

If extravasation is suspected, administration of the drug must be stopped immediately but the IV catheter left in place and the appropriate antidote instilled through the existing IV tube, after which the needle may be removed. The other options are incorrect.

 

DIF:    COGNITIVE LEVEL: Applying (Application)                  REF:   p. 736

TOP:   NURSING PROCESS: Implementation

MSC:  NCLEX: Safe and Effective Care Environment: Management of Care