Chapter 07: Neoplasia

Chapter 07: Neoplasia

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. Which of the following tumors occurs most often in the ovary?
2. Chondroma
3. Hemangioma
4. Leiomyoma
5. Transitional cell papilloma
6. Cystadenoma

ANS: E, Cystadenomas, which may contain serous fluid or mucin and are thus called serous or mucinous cystadenomas, are typically found in the ovary. These benign tumors have malignant counterparts known as cystadenocarcinomas.

2. Which one of the following carcinomas is locally invasive but rarely forms metastases in lymph nodes and distant sites?
3. Basal cell carcinoma of the skin
4. Squamous cell carcinoma of the skin
5. Oat cell carcinoma of the lung
6. Transitional cell carcinoma of the urinary bladder
7. Adenocarcinoma of the stomach

ANS: A, Basal cell carcinomas of the skin, the most common malignant tumor in the human body, is a locally invasive malignant tumor, which, if untreated, could ultimately kill the host. However, these tumors are usually diagnosed early and removed adequately, so that they almost never metastasize.

3. Pseudomyxoma peritonei is a complication of which tumor?
4. Serous cystadenoma of the ovary
5. Mucinous cystadenoma of the ovary
6. Ovarian fibroma
7. Myxoma of the heart
8. Myxosarcoma of the lower extremity

ANS: B, Pseudomyxoma of the ovary usually results from peritoneal seeding of mucin-secreting tumors of the ovary or the gastrointestinal tract, and most often the appendix. Although the ovarian tumor is benign, the implants of the tumor cells seeding the peritoneal cavity can be difficult to eradicate. The cells continue to secrete mucin and fill the abdominal cavity, colloquially known as “jelly-belly.”

4. Which mechanism affecting the genes or chromosomes accounts for the activation of the c-myc protooncogene in Burkitt lymphoma cells?
5. Overexpression
6. Amplification
7. Point mutation
8. Translocation
9. Inactivation of its promotor

ANS: D, Translocation of the c-myc protooncogene from its normal site on chromosome 8 to chromosome 14 results in the formation of the myc oncogene and plays a major role in the pathogenesis of Burkitt lymphoma.