Pathophysiology, 5th Edition By Lee-Ellen C. Copstead
Pathophysiology, 5th Edition By Lee-Ellen C. Copstead
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Chapter 12: HIV Disease and AIDS
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | HIV is not immunogenic. |
| b. | B cells are unable to produce antibodies against HIV. |
| c. | HIV mutates frequently. |
| d. | reverse transcriptase cleaves to the vaccine. |
ANS: C
The variability between strains of HIV and the frequency of mutations makes it difficult to produce a vaccine. HIV infection does not overwhelm the immune system, because it is an immune deficiency. Research is still being conducted to develop a vaccine. Researchers are testing cloned T-cells for response to new therapies. Reverse transcriptase is not proven to adhere to the vaccine.
REF: Pg. 254
| a. | has AIDS. |
| b. | has less than 2 years to live. |
| c. | cannot be treated. |
| d. | was an intravenous drug abuser. |
ANS: A
Pneumocystis carinii pneumonia (PCP) is a common initial opportunistic infection in HIV and is an AIDS-defining diagnosis. A diagnosis of PCP is not associated with a life-expectancy of 2 years or less. PCP is treated with antibiotic therapy. PCP is a pulmonary manifestation of AIDS, which is not associated with intravenous drug abuse.
REF: Pg. 247
| a. | an overactive B-cell system. |
| b. | proliferation of immature WBCs (blasts). |
| c. | deficiency of T-helper lymphocytes. |
| d. | cancerous growth of lymph tissue. |
ANS: C
HIV has been identified as a type of retrovirus associated with a disorder of the T-helper lymphocytes. T-cells have an interaction with B-cells, but this relationship is not associated with HIV. Immature blast cells are not the deficiency that contributes to HIV. Cancerous growths of lymphatic tissue have not been found to be the source of HIV.
REF: Pg. 233
| a. | AIDS is caused by a retrovirus and transmitted through body fluids. |
| b. | The mechanism of AIDS transmission is unknown; therefore, AIDS is considered to be highly contagious. |
| c. | AIDS is an autoimmune disease triggered by a homosexual lifestyle. |
| d. | AIDS is caused by a virus that can be transmitted only by sexual contact. |
ANS: A
AIDS is caused by an infection of HIV, which is proven to be transmitted through blood and body fluids. The mechanism of HIV transmission is known to be through blood and body fluid exposure, newborn infection from the mother, and unprotected sex with an infected partner. AIDS is not an autoimmune disease of the homosexual. HIV can be transmitted through unprotected intercourse. HIV is a virus that is transmitted through various routes, not sexual contact only.
REF: Pgs. 236-237
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