Chapter 13: Alterations in Oxygen Transport

Chapter 13: Alterations in Oxygen Transport

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. The primary source of erythropoietin is provided by the

ANS:  B

Erythropoietin is a hormone that is secreted into the bloodstream by the kidney. Bone marrow is not responsible for the production of erythropoietin. Hypoxia from low hemoglobin levels causes a decrease in tissue oxygen tension in the kidney, thereby releasing the hormone erythropoietin. The liver is not associated with erythropoietin production.

REF:   Pg. 261

2. Which condition is associated with an elevated reticulocyte count?

ANS:  D

Hemolytic anemia is associated with an increased number of circulating reticulocytes or reticulocytosis. Anemia of chronic renal failure is not associated with reticulocytosis. Rather, it occurs from failure of the renal endocrine function. Aplastic anemia is a stem cell disorder that is characterized by pancytopenia, a decrease in red cells, white cells, and platelets. Hypertension is not related to reticulocytosis.

REF:   Pg. 280

3. The strength of the bond between oxygen and hemoglobin is known as the

ANS:  B

The strength of the bond between oxygen and hemoglobin is called the oxygen-hemoglobin affinity. Hemoglobin saturation is higher when oxygen infinity is increased, and saturation is lower when affinity is decreased. The Bohr effect occurs when the oxyhemoglobin dissociation curve experiences a shift due to changes in PCO₂ and H+ concentration. The dissociation curve describes the relationship between the partial pressure of oxygen and hemoglobin saturation. Hemoglobin synthesis occurs in the immature red cell.

REF:   Pg. 265

4. An increase in hemoglobin affinity for oxygen occurs with

ANS:  D

An increase in oxygen affinity is known as a shift to the left on the dissociation curve. Hyperthermia does not have an effect on the hemoglobin affinity. Elevation in PCO₂ is seen with changes in pH. A decrease in the oxygen affinity is associated with a shift to the right on the oxyhemoglobin dissociation curve.

REF:   Pg. 267