Chapter 13: Central and Peripheral Nervous System Medications

Introduction To Clinical Pharmacology 8th Edition by Marilyn Winterton Edmunds

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Chapter 13: Central and Peripheral Nervous System Medications

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. What is the mechanism of action for antimigraine agents?
a. Blocking parasympathetic nerve impulses
b. Increasing cerebral blood flow
c. Constricting dilated cerebral arteries
d. Exerting a sympathomimetic effect

 

 

ANS:  C

Adrenergic-blocking agents dilate the veins in smooth-muscle tissue in the peripheral vascular system and the uterus. This reduces cerebral blood flow and arterial pulsing, which reduces the headache pain.

 

DIF:    Cognitive Level: Understand            REF:   pp. 242-243| Table 13-1

OBJ:   3                    TOP:   Antimigraine Agents                       KEY:  Nursing Process Step: N/A

MSC:  NCLEX: N/A

 

  1. The nurse is instructing a patient about the use of her oral antimigraine agent. The instruction should include the best effective action of the drug. Which represents the best way to take this agent?
a. Take the medication at the onset of an attack.
b. This medication should be taken 30 minutes after the onset of the migraine.
c. Take the medication routinely every night.
d. Take the medication 30 minutes before meals.

 

 

ANS:  A

If antimigraine agents are used at the onset of an attack, the ability of the drugs to relieve migraine pain and symptoms is increased.

 

DIF:    Cognitive Level: Apply                   REF:   p. 244             OBJ:   4

TOP:   Antimigraine Agents                       KEY:  Nursing Process Step: Implementation

MSC:  NCLEX: Safe, Effective Care Environment: Coordinated Care

 

  1. A patient comes to the clinic and tells the nurse she might be pregnant. She has migraine headaches. The physician prescribes dihydroergotamine (DHE 45). The nurse explains to the patient that this drug is being used for which reason?
a. This agent dilates vessels.
b. This agent does not have oxytocic effects.
c. This agent has no toxic effects.
d. This agent does not cause dependence.

 

 

ANS:  B

The drug causes cerebral vasculature to constrict, but it does not have an oxytocic effect and can be used during pregnancy.

 

DIF:    Cognitive Level: Apply                   REF:   p. 245 | Table 13-2

OBJ:   3                    TOP:   Antimigraine Agents

KEY:  Nursing Process Step: Implementation

MSC:  NCLEX: Physiological Integrity

 

  1. CNS depression, decreased respiratory rate, constricted pupils, tachycardia, and areflexia are symptoms of overdose with which drugs?
a. Barbiturates
b. Serotonin (5HT) receptor agonists
c. Dopaminergic agents
d. Anticholinergic drugs

 

 

ANS:  A

In CNS depression due to barbiturate overdose, there is slow, shallow respiration, miosis, tachycardia, areflexia (absence of reflexes), shock or coma, then death.

 

DIF:    Cognitive Level: Analyze                REF:   p. 249             OBJ:   4

TOP:   Barbiturates    KEY:  Nursing Process Step: Assessment

MSC:  NCLEX: Physiological Integrity

 

  1. Which is the drug of choice for status epilepticus?
a. Tegretol
b. Phenobarbital
c. Klonopin
d. Valium

 

 

ANS:  D

Diazepam (Valium) is used intravenously to control seizures and is the drug of choice for treatment of status epilepticus.

 

DIF:    Cognitive Level: Remember            REF:   p. 249             OBJ:   1

TOP:   Benzodiazepines                             KEY:  Nursing Process Step: N/A

MSC:   NCLEX: Physiological Integrity: Reduction of Risk Potential

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