Pathophysiology The Biologic Basis for Disease in Adults and Children, 7th Edition by Kathryn L.
Pathophysiology The Biologic Basis for Disease in Adults and Children, 7th Edition by Kathryn L.
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Chapter 14: Cancer in Children
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | Down syndrome | c. | Retinoblastoma |
| b. | Wilms tumor | d. | Neuroblastoma |
ANS: A
Trisomy 21 (Down syndrome) is the most common genetic defect linked to the development of acute leukemia. Children with Down syndrome have a 10- to 20-fold increased risk of developing acute lymphoblastic and myelogenous leukemia and a higher risk for developing acute megakaryocytic leukemia. No current research supports a link between the other stated congenital malformations and acute leukemia.
PTS: 1 REF: Page 444
| a. | During infancy | c. | After diagnosis of a chronic illness |
| b. | At peak times of physical growth | d. | After an acute illness |
ANS: B
Childhood cancers are most often diagnosed during peak times of physical growth. No current research supports the other options.
PTS: 1 REF: Page 443
| a. | Breast cancer | c. | Vaginal cancer |
| b. | Leukemia | d. | Lymphoma |
ANS: C
DES has been identified as a transplacental chemical carcinogen; a small percentage of the daughters of women who took DES during pregnancy developed adenocarcinomas of the vagina. No current research supports a link between the drug and other cancers.
PTS: 1 REF: Page 445
| a. | 40% | c. | 60% |
| b. | 50% | d. | 80% |
ANS: D
Currently, more than 80% of children diagnosed with cancer are cured.
PTS: 1 REF: Page 445
| a. | Epithelium | c. | Embryologic ectodermal layer |
| b. | Mesodermal germ layer | d. | Viscera |
ANS: B
Most childhood cancers originate from the mesodermal germ layer that gives rise to connective tissue, bone, cartilage, muscle, blood, blood vessels, gonads, kidney, and the lymphatic system. The other options are not common sites from which cancers originate.
PTS: 1 REF: Page 443
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