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Chapter 14- Drug Therapy to Decrease Pain, Fever, and Inflammation
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
| 1. | A patient is receiving acetaminophen (Tylenol) for fever. The patient also has inflammation in the knees and elbows with pain. Why will acetaminophen (Tylenol) assist in reducing fever but not in decreasing the inflammatory process? | |
| A) | Prostaglandin inhibition is limited to the central nervous system. | |
| B) | Acetaminophen inhibits cyclooxygenase (COX-1 and COX-2) only. | |
| C) | Acetaminophen has an antiplatelet effect to decrease edema. | |
| D) | Prostaglandins decrease the gastric acid secretion. | |
| Ans: | A | |
| Feedback: | ||
| The action of acetaminophen on prostaglandin inhibition is limited to the central nervous system. Aspirin and other nonselective NSAIDs inhibit COX-1 and COX-2. Acetaminophen does not produce an antiplatelet effect. Prostaglandins do not affect gastric secretions. | ||
| 2. | A patient suffers from pain in the elbow related to inflammation. What are the chemical mediators of inflammation? | |
| A) | Insulin, thyroid hormone, and calcitonin | |
| B) | Bradykinin, histamine, and leukotrienes | |
| C) | Phospholipids, arachidonic acid, and platelets | |
| D) | Red blood cells, lymph, and serosa | |
| Ans: | B | |
| Feedback: | ||
| Prostaglandins sensitize pain receptors and increase the pain associated with other chemical mediators of inflammation and immunity, such as bradykinin, histamine, and leukotrienes. Insulin, thyroid hormone, and calcitonin are not chemical mediators of inflammation. Phospholipids, arachidonic acid, and platelets are not chemical mediators of inflammation. Red blood cells, lymph, and serosa are not chemical mediators of inflammation. | ||
| 3. | A patient is administered acetylsalicylic acid (aspirin) for fever and headache. What is the action of acetylsalicylic acid (aspirin)? | |
| A) | Inhibiting prostaglandin synthesis in the central and peripheral nervous system | |
| B) | Providing selective action by inhibiting prostaglandin synthesis in the CNS | |
| C) | Inhibiting the release of norepinephrine to increase blood pressure | |
| D) | Suppressing the function of the hypothalamus to decrease inflammation | |
| Ans: | A | |
| Feedback: | ||
| Aspirin inhibits prostaglandin synthesis in the central nervous system and the peripheral nervous system. Acetylsalicylic acid does not provide selective action by inhibiting prostaglandin synthesis in the CNS. Aspirin does not inhibit the release of norepinephrine to increase blood pressure. Aspirin does not suppress the function of the hypothalamus to decrease inflammation. | ||
| 4. | When acetylsalicylic acid (aspirin) is administered in low doses, it blocks the synthesis of thromboxane A2. What physiological effect results from this action? | |
| A) | Inflammation is relieved. | |
| B) | Core body temperature is reduced. | |
| C) | Pain is relieved. | |
| D) | Platelet aggregation is inhibited. | |
| Ans: | D | |
| Feedback: | ||
| At low doses, aspirin blocks the synthesis of thromboxane A2 to inhibit platelet aggregation; this lasts for the life of the platelet. | ||
| 5. | A patient began taking acetylsalicylic acid (aspirin) several years ago to prevent platelet aggregation following a myocardial infarction. Which dose of aspirin is most likely appropriate for this patient? | |
| A) | 80 mg | |
| B) | 180 mg | |
| C) | 325 mg | |
| D) | 650 mg | |
| Ans: | A | |
| Feedback: | ||
| The dose of aspirin given depends mainly on the condition being treated. Low doses (325 mg initially and 80 mg daily) are used for the drug’s antiplatelet effects in preventing arterial thrombotic disorders such as myocardial infarction and stroke. | ||
Original price was: $30.00.$20.00Current price is: $20.00.
Original price was: $30.00.$20.00Current price is: $20.00.
Original price was: $30.00.$20.00Current price is: $20.00.
Original price was: $30.00.$20.00Current price is: $20.00.
Original price was: $30.00.$20.00Current price is: $20.00.
Original price was: $30.00.$20.00Current price is: $20.00.