Chapter 14: Noradrenergic transmission

Rang & Dale's Pharmacology by Humphrey P. Rang

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Chapter 14: Noradrenergic transmission

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. An intravenous infusion of norepinephrine typically

 

  1. increases peripheral resistance and heart rate
  2. decreases peripheral resistance and heart rate
  3. increases peripheral resistance and decreases heart rate
  4. decreases peripheral resistance and increases heart rate
  5. has no consistent effect on peripheral resistance and heart rate

 

Answer c: increases peripheral resistance and decreases heart rate

 

  1. In the liver, epinephrine acts via adrenergic beta-2 receptors to

 

  1. stimulate both phosphorylase and glycogen synthase
  2. inhibit both phosphorylase and glycogen synthase
  3. inhibit phosphorylase and stimulate glycogen synthase
  4. stimulate phosphorylase and inhibit glycogen synthase
  5. stimulate phosphorylase, glycogen synthase, and lipase

 

Answer d: stimulate phosphorylase and inhibit glycogen synthase

 

  1. Which drug inhibits the transport of norepinephrine into synaptic vesicles, thereby leading to neurotransmitter depletion?

 

  1. reserpine
  2. methyldopa
  3. bretylium
  4. 6-hydroxydopamine
  5. guanethidine

 

Answer a: reserpine

 

  1. Doxazosin is an example of a

 

  1. nonselective alpha-adrenoceptor antagonist
  2. selective alpha-1 adrenoceptor antagonist
  3. selective alpha-2 adrenoceptor antagonist
  4. selective alpha-1 adrenoceptor agonist
  5. selective alpha-2 adrenoceptor agonist

 

Answer b: selective alpha-1 adrenoceptor antagonist

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