Chapter 15: Drugs Used for Parkinson’s Disease

Basic Pharmacology For Nurses,15th Edition by Bruce D. Clayton

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Chapter 15: Drugs Used for Parkinson’s Disease

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. Which reaction occurs as a result of prescribing carbidopa-levodopa?
A. Idiosyncratic
B. Additive
C. Hypersensitivity
D. Tolerance

 

 

ANS:   B

 

  Feedback
A An idiosyncratic reaction produces unintended outcomes that are usually the opposite of the intended reaction.
B An additive reaction occurs when two medications are prescribed together with the knowledge that combining these medications will produce a therapeutic benefit unavailable if each were prescribed alone.
C A hypersensitive reaction is an unintended outcome and is usually characterized by dermatologic and respiratory symptoms.
D Developing tolerance to a drug means that over time, a greater amount is required to achieve the desired effect.

 

 

DIF:    Cognitive Level: Comprehension      REF:    232

TOP:    Nursing Process Step: Implementation

MSC:   NCLEX Client Needs Category: Physiological Integrity

 

  1. Which adverse effects associated with levodopa therapy would support the nursing diagnosis Risk for Injury?
A. Nausea and vomiting
B. Orthostatic hypotension
C. Anorexia and depression
D. Tachycardia and palpitations

 

 

ANS:   B

 

  Feedback
A Although nausea and vomiting are adverse effects of levodopa, they do not contribute to a risk for falling.
B When initiating levodopa therapy, orthostatic hypotension may occur. Although generally mild, patients may experience dizziness and weakness. Symptoms usually resolve within 1 or 2 weeks once tolerance is developed to the levodopa therapy. Orthostatic hypotension increases the risk for injury in Parkinson’s patients because they are also experiencing alterations in gait patterns.
C Although anorexia and depression are common adverse effects of levodopa, they do not contribute to a risk for falling.
D Tachycardia and palpitations are not common adverse effects of levodopa.

 

 

DIF:    Cognitive Level: Application             REF:    233

TOP:    Nursing Process Step: Diagnosis

MSC:   NCLEX Client Needs Category: Safe, Effective Care Environment

 

  1. Which vitamin will reduce the therapeutic effects of levodopa?
A. A
B. B6
C. C
D. D

 

 

ANS:   B

 

  Feedback
A Vitamin A does not affect therapy with levodopa.
B Pyridoxine (vitamin B6) will reduce the therapeutic effects of levodopa in oral doses of 5 to 10 mg or more. Generally, diets typically have less than 1 mg of vitamin B6 and therefore are not restricted. The ingredients in multivitamins, however, must be assessed.
C Vitamin C does not affect therapy with levodopa.
D Vitamin D does not affect therapy with levodopa.

 

 

DIF:    Cognitive Level: Comprehension      REF:    233

TOP:    Nursing Process Step: Planning

MSC:   NCLEX Client Needs Category: Physiological Integrity

 

  1. Which cholinergic symptoms of Parkinson’s disease are reduced with anticholinergic drugs?
A. Cognitive impairments
B. Rigidity
C. Tremors and drooling
D. Postural abnormalities

 

 

ANS:   C

 

  Feedback
A Anticholinergic drugs do not affect cognitive impairments.
B Anticholinergics have little effect on rigidity.
C Anticholinergic drugs will reduce the severity of tremors and drooling in patients with Parkinson’s disease. Anticholinergics are most useful when used in combination with levodopa.
D Anticholinergics have little effect on postural abnormalities.

 

 

DIF:    Cognitive Level: Knowledge             REF:    237

TOP:    Nursing Process Step: Assessment

MSC:   NCLEX Client Needs Category: Physiological Integrity

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