Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew
Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew
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Chapter 16: Asthma and Chronic Obstructive Pulmonary Disease Medications
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | montelukast (Singulair) po daily. |
| b. | ipratropium bromide bid with albuterol. |
| c. | a low-dose inhaled corticosteroid (ICS), 2 puffs bid. |
| d. | a long-acting b-adrenergic agonist (LABA), 1 puff bid. |
ANS: C
This patient has symptoms of mild, persistent asthma. The preferred controller medication in adults and children with persistent asthma is a low-dose ICS. Montelukast is a leukotriene modifier, which may be considered as an alternative to a low-dose ICS but is not the first option to try. Ipratropium is often used during an acute exacerbation but not for long-term control. LABA medications are used in patients with moderate persistent symptoms.
DIF: Cognitive Level: Applying (Application) REF: 210
| a. | order a high-dose ICS plus a LABA twice daily. |
| b. | consider adding theophylline to this patient’s regimen. |
| c. | continue the current regimen and add omalizumab daily. |
| d. | order a combination product with ipratropium and albuterol. |
ANS: A
The patient has moderate persistent asthma not well controlled with the current regimen. The next step is to prescribe a high-dose ICS to be taken along with the LABA and to refer to an asthma specialist. Theophylline is recommended in the 5- to 11-year age group. Omalizumab is indicated if the patient has allergies. Ipratropium is used during acute exacerbations.
DIF: Cognitive Level: Applying (Application) REF: 210
| a. | reassure the patient that these symptoms will subside. |
| b. | prescribe a moderate-dose ICS twice daily. |
| c. | order a long-acting anticholinergic with albuterol twice daily. |
| d. | prescribe an albuterol metered-dose-inhaler, 2 puffs every 4 hours as needed. |
ANS: D
For patients with stable COPD having respiratory symptoms with FEV1 between 60% and 80% of predicted, inhaled bronchodilators may be used. COPD is not reversible, and the symptoms will not subside. ICS therapy or long-acting anticholinergics are recommended when FEV1 is less than 60%.
DIF: Cognitive Level: Applying (Application) REF: 212 – 213
| a. | oral corticosteroid. |
| b. | long-acting anticholinergic. |
| c. | long-acting oral theophylline. |
| d. | combination ICS/LABA inhaler. |
ANS: D
Providers should administer combination inhaled therapies for symptomatic patients with stable COPD and FEV1 less than 60%. Oral corticosteroids have not been shown to be effective, even in severe cases of COPD. Long-acting anticholinergic medications may be used as monotherapy in early stages of COPD. Long-acting theophylline is poorly tolerated because of side effects.
DIF: Cognitive Level: Applying (Application) REF: 213
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