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Chapter 16: Head and Neck

Robbins & Cotran Pathologic Basis of Disease 9th Edition by Vinay Kumar

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Chapter 16: Head and Neck

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. Stevens-Johnson syndrome is a form of which disease affecting the skin, lips, and the oral mucosa?
  2. Lichen planus
  3. Pemphigus
  4. Bullous pemphigoid
  5. Erythema multiforme
  6. Infectious mononucleosis

 

ANS: D, Stevens-Johnson syndrome is a form of erythema multiforme, which, in addition to the skin, involves the lips and mouth. Similar to erythema multiforme, it may represent a reaction to drugs or an infection elsewhere in the body. It may also be secondary to cancer or to an autoimmune disease.

 

  1. A nasal tumor was found in a 58-year-old man who complained of prolonged nasal discharge and occasional bleeding. The tumor was composed of solid nests of “small blue cells” that stained immunohistochemically with the antibodies to S100 protein. Electron microscopy revealed neuroendocrine cytoplasmic granules. Which of the following is the most likely diagnosis?
  2. Olfactory neuroblastoma
  3. Glioma
  4. Meningioma
  5. Lymphoma
  6. Nasal adenocarcinoma

 

ANS: A, “Small blue cell neoplasms” showing neural or neuroendocrine differentiation are called olfactory neuroblastomas.

 

  1. A 13-year-old boy complained of recurrent profuse nasal bleeding. He was examined by an otorhinolaryngologist who found a polypoid tumor in the nose. The pathologist reported the tumor as benign. This tumor was identified as a(n)
  2. hemangiopericytoma
  3. angiofibroma
  4. Kaposi sarcoma
  5. angiosarcoma
  6. inverted papilloma

 

ANS: B, An angiofibroma is a benign tumor composed of blood vessels embedded in fibrous stroma. It occurs almost exclusively in young males. Due to its vascularity, it can cause profuse bleeding.

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