Chapter 17: Local and Humoral Control of Tissue Blood Flow

Guyton And Hall Textbook of Medical Physiology 12e by John E. Hall

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Chapter 17: Local and Humoral Control of Tissue Blood Flow

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

  1. A healthy 25-year-old male medical student has an exercise stress test at a local health club. Which of the following set of physiological changes is most likely to occur in this man’s skeletal muscles during exercise?

Arteriole Diameter                  Adenosine Concentration       Tissue Metabolism

 

  1. ­                                              ­                                              ­
  2. ­                                              ¯                                              ­
  3. ­                                              ¯                                              ¯
  4. ­                                              ­                                              ¯
  5. ¯                                              ¯                                              ¯
  6. ¯                                              ­                                              ¯
  7. ¯                                              ­                                              ­
  8. ¯                                              ¯                                              ­

 

ANS: A

 

  1. The arterial pressure of an isolated perfused muscle is increased from 100 to 140 mmHg. Blood flow to the muscle at 100 mmHg is 5 ml/min/100 g and 5.1 ml/min/100 g at 140 mmHg. The maintenance of blood flow despite the large elevation in arterial pressure is due to an increase in which of the following?
  1. arterial conductance
  2. adenosine concentration
  3. arteriolar resistance
  4. lactic acid concentration
  5. nitric oxide concentration

 

ANS: C

 

  1. Autoregulation of tissue blood flow in response to an increase in arterial pressure occurs as a result of
  1. a decrease in vascular resistance
  2. an initial decrease in vascular wall tension
  3. excess delivery of nutrients such as oxygen to the tissues
  4. a decrease in tissue metabolism

 

ANS: C

 

 

 

  1. Histamine is injected into the brachial artery of a 25-year-old man. Which of the following sets of changes would be expected to occur in response to histamine?

Vascular                    Vascular                                   Capillary

Resistance                 Conductance                            Filtration

  1.             ­                                  ­                                              ­
  2.             ­                                  ¯                                              ­
  3.             ¯                                  ¯                                              ¯
  4.             ¯                                  ­                                              ­
  5.             ¯                                  ¯                                              ­

ANS: D

 

  1. A 72-year-old male had surgery to remove an abdominal tumor. Pathohistological studies reveal that the tumor mass contains a large number of vessels. An increase in which of the following is the most likely stimulus for the growth of vessels in a solid tumor?
  2. growth hormone
  3. plasma glucose concentration
  4. angiostatin growth factor
  5. tissue oxygen concentration
  6. vascular endothelial growth factor

 

ANS: E

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