Ford Roach's Introductory Clinical Pharmacology 9th Edition by Susan M. Ford
Ford Roach's Introductory Clinical Pharmacology 9th Edition by Susan M. Ford
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Chapter 17- Opioid Antagonists
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
| 1. | Which of the following are true in regards to opioid antagonist? Select all that apply: | |
| A) | An opioid antagonist has greater affinity for opioid receptors than do opioid agonists. | |
| B) | An opioid antagonist has lesser affinity for opioid receptors than do opioid agonists. | |
| C) | An opioid antagonist prevents a response to the opioid by binding to opioid agonists in the bloodstream. | |
| D) | An opioid antagonist prevents a response to the opioid by binding to opioid receptors. | |
| E) | An opioid antagonist potentiates the effect of an opioid. | |
| 2. | Which of the following would a nurse most likely be ordered to give to a client experiencing opioid-induced respiratory depression? Select all that apply: | |
| A) | Naloxone (Narcan) | |
| B) | Nalmefene (Revex) | |
| C) | Naltrexone (Depade) | |
| D) | Naproxen (Naprosyn) | |
| E) | Nitroglycerin (Nitrostat) | |
| 3. | Which of the following represent the mechanism by which opioid antagonists reverse the effects of opioid agonists? Select all that apply: | |
| A) | Competitive inhibition of the opioid receptor | |
| B) | Direct binding to the opioid agonist | |
| C) | Displacement of the opioid agonist from the opioid receptor | |
| D) | Irreversible inhibition of the opioid receptor | |
| E) | Mutation of the opioid receptor | |
| 4. | An opioid antagonist will reverse which of the following opioid effects? Select all that apply: | |
| A) | Respiratory depression | |
| B) | Constipation | |
| C) | Analgesia | |
| D) | Hypotension | |
| E) | Bradycardia | |
| 5. | A client has just returned from the OR with orders from the physician for nalmefene (Revex) 0.25 mcg/kg. The client weighs 150 lb. How many mcg of nalmefene should the client receive? |
Answer Key
| 1. | A, D |
| 2. | A, B |
| 3. | A, C |
| 4. | A, B, C, D, E |
| 5. | 17 mcg |
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