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Chapter 18: Coronary Artery Disease and Antianginal Medications

Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew

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Chapter 18: Coronary Artery Disease and Antianginal Medications

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. A patient who has a history of angina has sublingual nitroglycerin tablets to use as needed. The primary care nurse practitioner (NP) reviews this medication with the patient at the patient’s annual physical examination. Which statement by the patient indicates understanding of the medication?
a. “I should call 9-1-1 if chest pain persists 5 minutes after the first dose.”
b. “I should take 3 nitroglycerin tablets 5 minutes apart and then call 9-1-1.”
c. “I should take aspirin along with the nitroglycerin when I have chest pain.”
d. “I should take nitroglycerin and then rest for 15 minutes before taking the next dose.”

 

 

ANS:  A

Although the traditional recommendation is for patients to take up to 3 nitroglycerin doses over 15 minutes before accessing emergency medical services (EMS), more recent guidelines suggest an alternative strategy to reduce delays in emergency care. These include instructions to call 9-1-1 immediately if pain persists for 5 minutes after the first dose. Aspirin is recommended when the patient is being transported to emergency care and is not recommended as an adjunct to nitroglycerin with each episode of chest pain. The three doses of nitroglycerin are given 5 minutes apart over 15 minutes.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   241

 

  1. A patient who will begin using nitroglycerin for angina asks the primary care NP how the medication works to relieve pain. The NP should tell the patient that nitroglycerin acts to:
a. dissolve atheromatous lesions.
b. relax vascular smooth muscle.
c. prevent catecholamine release.
d. reduce C-reactive protein levels.

 

 

ANS:  B

Nitrates relax vascular smooth muscle via stimulation of intracellular cyclic guanosine monophosphate production with the major effect being to reduce myocardial oxygen demand. Nitrates do not dissolve atheromatous lesions, prevent catecholamine release, or reduce C-reactive protein levels.

 

DIF:    Cognitive Level: Understanding (Comprehension)             REF:   239 – 240

 

  1. A patient who has angina uses 0.4 mg of sublingual nitroglycerin for angina episodes. The patient brings a log of angina episodes to an annual physical examination. The primary care NP notes that the patient has experienced an increase in frequency of episodes in the past month but no increase in duration or severity of pain. The NP should:
a. increase the nitroglycerin dose to 0.6 mg per dose.
b. change from a sublingual to a transdermal patch nitroglycerin.
c. discontinue the nitroglycerin and order ranolazine (Ranexa ER).
d. contact the patient’s cardiologist to discuss admission to the hospital.

 

 

ANS:  D

Unstable angina is a change in pattern or pain, such as an increase in frequency, severity, or duration of pain and fewer precipitating factors. Patients with unstable angina should be admitted to a coronary care unit. The primary care NP should not change any medications without consultation with the patient’s cardiologist.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   239

 

  1. A patient who has stable angina and uses sublingual nitroglycerin tablets is in the clinic and begins having chest pain. The primary care NP administers a nitroglycerin tablet and instructs the patient to lie down. The NP’s next action should be to:
a. obtain an electrocardiogram.
b. administer oxygen at 2 L/minute.
c. give 325 mg of chewable aspirin.
d. call EMS.

 

 

ANS:  B

When a patient experiences an acute attack of angina in the clinic, the primary care NP should be prepared to treat the condition. After giving nitroglycerin, oxygen should be administered. An electrocardiogram is not immediately indicated. Chewable aspirin is given if the angina is unrelieved and when the patient is being transported to the hospital. EMS should be activated if there is no pain relief 5 minutes after the first dose of nitroglycerin.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   241

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