Chapter 19: Peptides and proteins as mediators

Rang & Dale's Pharmacology by Humphrey P. Rang

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Chapter 19: Peptides and proteins as mediators

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. Peptide and protein mediators typically

 

  1. function as fast neurotransmitters
  2. contain intramolecular diphosphate bonds
  3. are easily crystallized
  4. have highly rigid structures
  5. activate cell surface receptors

 

Answer e: activate cell surface receptors

 

  1. As pharmacologic agents, most peptides are

 

  1. easily absorbed from the gastrointestinal tract
  2. rapidly distributed to the brain
  3. usually administered by the transdermal route
  4. rapidly degraded by plasma and tissue enzymes
  5. inexpensive to manufacture

 

Answer d: rapidly degraded by plasma and tissue enzymes

 

  1. Bosentan is an antagonist of

 

  1. opioid receptors
  2. angiotensin AT1 receptors
  3. endothelin receptors
  4. bradykinin receptors
  5. platelet fibrinogen receptors

 

Answer c: endothelin receptors

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