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Chapter 2. Basics of Pharmacology

Pharmacology Clear And Simple A Guide to Drug 2nd Edition By Watkins

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Chapter 2. Basics of Pharmacology

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

Multiple Choice

Identify the choice that best completes the statement or answers the question.

 

____     1.   The nurse is preparing to apply valacyclovir (Valtrex) ointment to the shingles lesions located across a client’s left side and lower back. Which of the following actions should the nurse take first?

A. Place the patient in a supine position.
B. Determine when the rash was first noted.
C. Ensure that the skin is clean and dry.
D. Take the patient’s vital signs.

 

 

____     2.   The nurse is providing care for a client at 32 weeks’ gestation who started low-molecular heparin injections after developing a deep vein thrombosis. The client asks the nurse, “Why do I have to take a shot? Why can’t I take the blood clot medicine that my dad takes orally?” Which of the following responses by the nurse is best?

A. “Anything that is fat-soluble, including warfarin (Coumadin), is able to cross the placental barrier. Heparin is not fat-soluble so it doesn’t cross the barrier well.”
B. “The placenta is easily crossed by anything you take by mouth while you are pregnant, but not by things absorbed in other ways.”
C. “Only water-soluble substances such as vitamins can cross the placental barrier, so you could take either medication, but heparin is cheaper.”
D. “They are the same medication, but the shot is absorbed faster than the pill so the doctor wants you to take daily shots.”

 

 

____     3.   The nurse is providing care to a client with HIV who has been prescribed fosamprenavir (Lexiva). Which of the following statements by the client indicates that further teaching is necessary?

A. “The metabolites of this medication may be excreted in active form.”
B. “I’m glad my kidneys work so well; otherwise the medication wouldn’t work.”
C. “This drug actually has to be broken down by my body to fight the virus.”
D. “Isn’t it fascinating that my liver has to metabolize the drug for it to work?”

 

 

____     4.   The nurse is working with a client who was recently started on insulin therapy. The client’s young daughter asks, “Why do you have to give her a shot? Why can’t you just give her a pill?” Which of the following responses by the nurse is best?

A. “Our bodies make insulin normally, so it is a liquid medication.”
B. “We do have diabetic medications in pill form. I’m not sure why the doctor ordered it this way for your mom.”
C. “Insulin is manufactured and given this way so it absorbs more rapidly into the body.”
D. “The acid in your mother’s stomach would destroy this medication, so it can’t be swallowed.”

 

Answer Section

 

MULTIPLE CHOICE

 

  1. ANS:  C                    PTS:   1                    DIF:    Moderate

TOP:   Therapeutic Classification: Medication Provision; antivirals

KEY:  Analysis         MSC:  NCLEX Category: Pharmacological Therapies

NOT:  See Absorption (p. 15). When administering an ointment for a rash, make sure the skin is clean and dry.

 

  1. ANS:  A                    PTS:   1                    DIF:    Moderate

TOP:   Therapeutic Classification: Anticoagulant therapy              KEY:  Analysis

MSC:  NCLEX Category: Pharmacological Therapies

NOT:  See Distribution (p. 16): The blood-placental barrier helps to filter drugs and other substances passing from mother to fetus. Most lipid-soluble drugs readily cross this barrier but water-soluble drugs do not. Warfarin (Coumadin) is fat-soluble and crosses the placental barrier while heparin does not. They are not the same medication and cost is not part of the therapeutic decision.

 

  1. ANS:  B                    PTS:   1                    DIF:    Moderate

TOP:   Therapeutic Classification: Medication Administration; antivirals

KEY:  Analysis         MSC:  NCLEX Category: Pharmacological Therapies

NOT:  See Metabolism (p. 16): The liver does most of the work of drug metabolism. In some instances, a drug is administered in its inactive form to become activated through metabolism. This category of drugs is known as prodrugs. An example of a prodrug is fosamprenavir (Lexiva).

 

  1. ANS:  D                    PTS:   1                    DIF:    Moderate

TOP:   Therapeutic Classification: Antidiabetics                           KEY:  Analysis

MSC:  NCLEX Category: Pharmacological Therapies

NOT:  See Metabolism (p. 16): Insulin given by mouth is virtually useless; stomach acid breaks down insulin to an inactive form before it can be absorbed into the bloodstream. Oral diabetic medications are not forms of insulin; they stimulate the pancreas to release insulin.

 

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