Basic Pharmacology For Nurses,15th Edition by Bruce D. Clayton
Basic Pharmacology For Nurses,15th Edition by Bruce D. Clayton
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Chapter 2: Principles of Drug Action and Drug Interactions
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| A. | Notify physician of allergic reaction. |
| B. | Notify physician of idiosyncratic reaction. |
| C. | Notify physician of potential teratogenicity. |
| D. | Notify physician of potential tolerance. |
ANS: A
| Feedback | |
| A | Allergic reactions are a hypersensitivity and manifest with hives and/or urticaria and are easily identified. |
| B | An idiosyncratic reaction occurs when something unusual or abnormal happens when a drug is first administered. |
| C | A teratogenic reaction refers to the occurrence of birth defects related to administration of the drug. |
| D | Tolerance refers to the body’s requirement for increasing dosages to achieve the same effects that a lower dose once did. |
DIF: Cognitive Level: Comprehension REF: 21
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
| A. | Desired action |
| B. | Adverse effect |
| C. | Idiosyncratic reaction |
| D. | Allergic reaction |
ANS: C
| Feedback | |
| A | Desired actions are expected responses to a medication. |
| B | Adverse effects are reactions that occur in another system of the body; they are usually predictable. |
| C | Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first administered. Patients typically exhibit an overresponsiveness to a medication related to diminished metabolism. These reactions are believed to be related to genetic enzyme deficiencies. |
| D | Allergic reactions appear after repeated medication dosages |
DIF: Cognitive Level: Comprehension REF: 21
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity
| A. | Drug toxicity related to overmedication |
| B. | Drug buildup related to decreased metabolism |
| C. | The inability to control the ingestion of drugs |
| D. | The need for higher dosage to produce the same effect as previous lower dosages |
ANS: B
| Feedback | |
| A | Toxicity occurs when adverse effects are severe. |
| B | Cumulative effects are related to diminished metabolism or excretion of a drug that causes it to accumulate. Cumulative effects can lead to drug toxicity. |
| C | Inability to control the ingestion of drugs is drug dependence. |
| D | The need for higher dosage to produce the same effect as previous lower dosages is the definition of tolerance. |
DIF: Cognitive Level: Knowledge REF: 23
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
| A. | On administration of toxic dosages of a drug |
| B. | On an increase in the pharmacodynamics of bound drugs |
| C. | On the alteration of the effect of one drug by another drug |
| D. | On increase of drug excretion |
ANS: C
| Feedback | |
| A | Toxicity of one drug may or may not affect the metabolism of another one. |
| B | Drug interactions may result from either increased or decreased pharmacodynamics. |
| C | Drug interactions may be characterized by an increase or decrease in the effectiveness of one or both of the drugs. |
| D | Drug interactions may result from either increased or decreased excretion. |
DIF: Cognitive Level: Comprehension REF: 23
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
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