Chapter 20: Drugs That Affect Blood Clotting

Understanding Pharmacology Essentials For Medication Safety By M. Linda Workman

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Chapter 20: Drugs That Affect Blood Clotting

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

BASIC CONCEPTS

 

  1. Which blood component forms the initial plug that helps stop bleeding?
a. Fibrin
b. Platelets
c. Neutrophils
d. Eosinophils

 

 

ANS:  B

While fibrin creates threads that make the plasma sticky and able to clot, it is platelets that clump together to create the initial plug that helps to stop bleeding. Neutrophils and eosinophils are types of white blood cells that help the body fight off infection.

 

DIF:    Cognitive Level: Remembering        REF:   p. 325

 

  1. Which patient factor increases the risk for bleeding during anticoagulant therapy?
a. Pregnancy
b. Recent major surgery
c. History of severe arthritis
d. Uncontrolled low blood pressure

 

 

ANS:  B

Recent major surgery results in damage to blood vessels. When blood vessels lose their integrity, bleeding results. It takes some time for blood vessels to heal after surgery, during which time the patient remains at risk for bleeding. When the patient is also given a drug that reduces blood clotting before all blood vessels have completely healed, the risk for bleeding is greatly increased.

 

DIF:    Cognitive Level: Remembering        REF:   p. 327

 

  1. What is the name of a blood clot that forms and stays within a blood vessel or the heart?
a. Antibus
b. Embolus
c. Thrombus
d. Coagulus

 

 

ANS:  C

Antibus and coagulus are not medical terms. An embolus is a clot that travels through the body and can lodge in a smaller blood vessel. A thrombus is a clot that usually forms within a blood vessel and stays there, often preventing blood from moving past that point.

 

DIF:    Cognitive Level: Remembering        REF:   p. 325

 

  1. Which category of drugs actually dissolves existing clots?
a. Heparins
b. Coagulants
c. Antiplatelets
d. Thrombolytics

 

 

ANS:  D

Heparin and antiplatelet drugs prevent clots from forming and also prevent existing clots from becoming larger. They do not dissolve existing clots. Coagulants would enhance blood clotting, not dissolve clots.

 

DIF:    Cognitive Level: Remembering        REF:   p. 325

 

  1. Which thrombin inhibitor can be given by subcutaneous injection?
a. Heparin
b. Argatroban
c. Lepirudin
d. Bivalirudin

 

 

ANS:  A

Argatroban, lepirudin, and bivalirudin are administered only intravenously. Heparin can be administered as an intravenous bolus, as a continuous intravenous infusion, or as a subcutaneous injection.

 

DIF:    Cognitive Level: Remembering        REF:   p. 328

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