Chapter 23: Drugs for Multiple Sclerosis

Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne

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Chapter 23: Drugs for Multiple Sclerosis

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

  1. A nurse is teaching a class of nursing students on the unit about the pathophysiology of multiple sclerosis. To evaluate their understanding, the nurse asks the students, “Which part of a neuron would be the most damaged in a patient with multiple sclerosis?” The students’ best response would be which of the following components of the nervous system?
a. Myelin sheath
b. Dendrite
c. Cell body
d. Nucleus

 

 

ANS:   A

Multiple sclerosis is a chronic, inflammatory, autoimmune disorder that damages the myelin sheath of neurons in the central nervous system.

Multiple sclerosis does not damage the dendrite, cell body, or nucleus.

 

DIF:    Cognitive Level: Comprehension      REF:    p. 206

TOP:    Nursing Process: Evaluation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Physiological Adaptation

 

  1. A patient with multiple sclerosis is admitted to the unit for an acute exacerbation and is given interferon beta-1a (Avonex). What questions related to adverse effects should the nurse include in the physical assessment?
a. “Are you experiencing any gastrointestinal upset or diarrhea?”
b. “Do you have a headache, chills, or muscle aches?”
c. “Are you having any swelling in your legs or shortness of breath?”
d. “Do you have or have you experienced any ringing in your ears?”

 

 

ANS:   B

Assessment of the patient should include assessing for flulike symptoms, which often are adverse effects associated with interferon beta-1a.

Interferon beta-1a does not have the adverse effect of gastrointestinal symptoms.

Swelling in the legs and shortness of breath may indicate cardiotoxicity, which is seen most often with mitoxantrone, not interferon beta-1a.

Tinnitus is not an adverse effect of interferon beta-1a.

 

DIF:    Cognitive Level: Analysis                  REF:    p. 210

TOP:    Nursing Process: Assessment

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

  1. A nurse administered glatiramer (Copaxone) just 10 minutes ago. The patient calls the nurses’ station to report itching. Upon assessment the nurse notes that the patient is flushed and has palpitations, anxiety, and chest pain. What action should the nurse take first?
a. Explain to the patient that the symptoms occur with some patients and will pass within 15 to 20 minutes.
b. Prepare to administer epinephrine, because the patient is experiencing the onset of anaphylaxis.
c. Prepare the crash cart.
d. Elevate the head of the bed, apply oxygen, and maintain the airway.

 

 

ANS:   A

About 10% of patients who receive glatiramer experience self-limited, postinjection reactions, characterized by flushing, palpitations, severe chest pain, anxiety, laryngeal constriction, and urticaria. The reaction typically does not last longer than 15 to 20 minutes, but the patient should be monitored.

The symptoms described are expected and do not indicate anaphylaxis, therefore epinephrine should not be administered.

The symptoms do not indicate an emergency situation, therefore the crash cart is not needed.

The symptoms do not indicate anaphylaxis, therefore no treatment is required at this time.

NCLEX Client Needs Category:

 

DIF:    Cognitive Level: Application             REF:    p. 211

TOP:    Nursing Process: Implementation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Reduction of Risk Potential

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