Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew
Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew
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Chapter 26: Antacids and the Management of GERD
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | a fundoplication will be necessary to correct the cause of GERD. |
| b. | over-the-counter (OTC) antacids can be effective and should be tried first. |
| c. | elevation of the head of the bed at night can relieve most symptoms. |
| d. | a combination of lifestyle changes, medications, and surgery may be necessary. |
ANS: D
People with GERD often have hiatal hernia, but this is not the cause of GERD. The approach to treatment of GERD may include lifestyle changes, medications, and surgery. OTC antacids are sometimes used but are rarely used as first-line treatment.
DIF: Cognitive Level: Applying (Application) REF: 329
| a. | can help to heal erosions in esophageal tissue. |
| b. | do not help reduce symptoms of erosive esophagitis. |
| c. | neutralize stomach acid as well as proton pump inhibitors (PPIs). |
| d. | help reduce symptoms in conjunction with PPIs. |
ANS: D
Antacids reduce symptoms but do not have a significant effect on healing of erosions or esophagitis. If the patient has severe symptoms, has found treatment for milder symptoms to be ineffective, or has experienced erosion that is documented by endoscopy, he or she should be started on a PPI.
DIF: Cognitive Level: Applying (Application) REF: 329
| a. | the dose may be decreased for long-term therapy. |
| b. | antireflux surgery must be done before the PPI can be discontinued. |
| c. | the condition may eventually be cured, but therapy must continue for years. |
| d. | once the symptoms have cleared completely, the medication may be discontinued. |
ANS: A
Once PPIs have proven clinically effective for treatment of patients with esophagitis, therapy should be continued long-term and titrated down to the lowest effective dose based on symptom control. PPI therapy is considered safer than surgery and should be tried first before surgery is performed. GERD is a lifelong syndrome and is not curable.
DIF: Cognitive Level: Applying (Application) REF: 329
| a. | antacid therapy as needed. |
| b. | changes in diet to avoid acidic foods. |
| c. | daily treatment with a PPI. |
| d. | consultation with a gastroenterologist for endoscopy. |
ANS: C
This patient has symptoms of GERD. PPIs are first-line medications for treating GERD and may be started empirically. Antacids are not first-line medications. Changes in diet are not recommended as treatment but may help with symptoms. Patients with symptoms unrelieved by PPIs should be referred for possible endoscopy.
DIF: Cognitive Level: Applying (Application) REF: 328
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