Porth's Pathophysiology, Concepts of Altered Health States 9th Edition by Sheila Grossman-Carol Mattson Porth
Porth's Pathophysiology, Concepts of Altered Health States 9th Edition by Sheila Grossman-Carol Mattson Porth
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Chapter 27- Disorders of Red Blood Cells
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
| 1. | A surgeon is explaining to the parents of a 6-year-old boy the rationale for the suggestion of removing the boy’s spleen. Which of the following teaching points would be most accurate? | |
| A) | “Ferritin is the activated and usable form of iron that your red blood cells can use to transport oxygen.” | |
| B) | “Ferritin is a stored form of iron that indirectly shows me whether you would benefit from iron pills.” | |
| C) | “Ferritin is a protein–iron complex that allows your red blood cells to make use of the iron that you consume in your diet.” | |
| D) | “Ferritin is the form of iron that is transported in your blood plasma to red blood cells that need it.” | |
| Ans: | B | |
| Feedback: | ||
| Ferritin is the protein–iron complex that is stored in tissues, especially the liver, and the serum levels can be used as an indicator of the need for iron supplements. It is not accurately characterized as an activated form of iron, nor does it mediate the actual use of iron by erythrocytes. Transferrin, not ferritin, is transported in plasma, and it is associated with iron storage. | ||
| 2. | A 62-year-old female with a diagnosis of acute and chronic renal failure secondary to diabetes mellitus is receiving her weekly injection of epoetin, a supplementary form of erythropoietin. Which of the following statements best captures the necessity of this medication? | |
| A) | Erythropoietin is needed in order for stem cells to proliferate into committed erythroid precursors. | |
| B) | Erythropoietin is necessary for the accurate sensation of hypoxia that stimulates erythropoiesis. | |
| C) | Erythropoietin causes the erythrocyte colony–forming units to proliferate and mature. | |
| D) | Erythropoietin facilitates the extrusion of the reticulocyte nucleus and the formation of true erythrocytes. | |
| Ans: | C | |
| Feedback: | ||
| Erythropoietin acts primarily in later stages of erythropoiesis to induce the erythrocyte colony–forming units to proliferate and mature through the normoblast stage into reticulocytes and mature erythrocytes. It does not act directly on the stem cells, nor does it play a role in the sensation of hypoxia. Reticulocytes already lack a cell nucleus. | ||
| 3. | A client with a diagnosis of hemolytic anemia has gone to a community-based laboratory for follow-up blood work. The lab technician confirms with the client that hematocrit is one of the components of the blood work. The client replies, “I thought the point of the blood work was to see how many red blood cells I have today.” How could the technician best respond to the client’s statement? | |
| A) | “This result will tell your care provider about the number of red blood cells in a given quantity of your blood plasma.” | |
| B) | “Your hematocrit measures the average size of your red blood cells and indirectly measures your oxygen-carrying capacity.” | |
| C) | “The result will indicate how many of your red blood cells are new and young and will indicate your body’s production rate of red cells.” | |
| D) | “The hematocrit measures the mass that your red blood cells account for in a quantity of your blood.” | |
| Ans: | D | |
| Feedback: | ||
| Hematocrit measures the mass of erythrocytes in a given quantity of blood plasma. It does not measure the number of red cells, their size, or their production rate and age. | ||
| 4. | A client with a gastrointestinal bleed secondary to alcohol abuse and a hemoglobin level of 5.8 g/dL has been ordered a transfusion of packed red blood cells. The client possesses type B antibodies but lacks type D antigens on his red cells. Transfusion of which of the following blood types would be least likely to produce a transfusion reaction? | |
| A) | B– | |
| B) | B+ | |
| C) | A+ | |
| D) | A– | |
| Ans: | D | |
| Feedback: | ||
| The client’s blood type is A– and would necessitate A– or O– donor blood. Other types would induce a transfusion reaction. | ||
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