Abrams' Clinical Drug Therapy Rationales for Nursing Practice by Geralyn Frandsen
Abrams' Clinical Drug Therapy Rationales for Nursing Practice by Geralyn Frandsen
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Chapter 30- Drug Therapy to Decrease Histamine Effects
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
| 1. | A patient is stung by a bee. What is the chemical mediator released in immune and inflammatory response to the bee sting? | |
| A) | Norepinephrine | |
| B) | Mast cells | |
| C) | Epinephrine | |
| D) | Histamine | |
| Ans: | D | |
| Feedback: | ||
| Histamine is the chemical mediator released in immune and inflammatory response to the bee sting. | ||
| 2. | A patient is experiencing allergy symptoms after being exposed to environmental dust. This reaction involves the action of histamine, which is released by what cells? | |
| A) | Lymphocytes | |
| B) | CD4 T cells | |
| C) | Basophils | |
| D) | Platelets | |
| Ans: | C | |
| Feedback: | ||
| Histamine is discharged from mast cells and basophils in response to certain stimuli, such as allergic reactions, cellular injury, and extreme cold. Lymphocytes and platelets do not release histamine. | ||
| 3. | A patient is being administered epinephrine for the treatment of anaphylaxis. This patient is experiencing what type of hypersensitivity reaction? | |
| A) | Type I | |
| B) | Type II | |
| C) | Type III | |
| D) | Type IV | |
| Ans: | A | |
| Feedback: | ||
| Anaphylaxis is a type I response, which can be mild or life threatening. | ||
| 4. | An elderly patient is given diphenhydramine (Benadryl) for allergic response to mold. The nurse should consequently assess the patient for | |
| A) | anticholinergic effects. | |
| B) | dysrhythmias. | |
| C) | increased muscle tone. | |
| D) | respiratory depression. | |
| Ans: | A | |
| Feedback: | ||
| Diphenhydramine (Benadryl) is the prototype of first-generation antihistamines and causes a high incidence of drowsiness and anticholinergic effects. It is not associated with dysrhythmias, increased muscle tone, or respiratory depression. | ||
| 5. | A second-generation H1 receptor antagonist antihistamine formulated as a nasal spray for topical use is | |
| A) | chlorpheniramine (Chlor-Trimeton). | |
| B) | clemastine (Tavist). | |
| C) | cyproheptadine (Periactin). | |
| D) | azelastine (Astelin). | |
| Ans: | D | |
| Feedback: | ||
| Azelastine (Astelin) and olopatadine (Patanol) are second-generation H1 receptor antagonists that have been formulated as nasal sprays for topical use. Each of the other listed drugs is a first-generation H1 receptor antagonist. | ||
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