Chapter 35- Hypothalamic and Pituitary Agents

Chapter 35- Hypothalamic and Pituitary Agents

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

1. A patient suspected of having Cushing’s disease comes to the clinic. What drug might the nurse
administer to test for adrenal function and responsiveness?
A) Corticotropin
B) Menotropins
C) Thyrotropin alfa
D) Chorionic gonadotropin
Ans: A
Feedback:
Corticotropin (ACTH) and cosyntropin are used for diagnostic purposes to test adrenal function and
responsiveness. Menotropin is a purified preparation of gonadotropins and is used as a fertility drug.
Thyrotropin alfa is used as adjunctive treatment for radioiodine ablation of thyroid tissue remnants in
patients who have undergone a near-total to total thyroidectomy for well-differentiated thyroid cancer
and who do not have evidence of metastatic thyroid cancer. Chorionic gonadotropin acts like
luteinizing hormone and stimulates the production of testosterone and progesterone.
2. A nurse is working at a fertility clinic. Today she is administering ganirelix acetate (Antagon) to a
woman participating in a fertility research program. By what route is this drug administered?
A) Orally
B) Subcutaneously
C) Intramuscularly
D) IV
Ans: B
Feedback:
Ganirelix acetate (Antagon) is administered subcutaneously and cannot be administered orally,
intramuscularly, or intravenously.
3. A patient is taking leuprolide (Lupron) to treat prostatic cancer. The nurse caring for this patient is
careful to monitor for what?
Test Bank – Focus on Nursing Pharmacology (7th Edition by Amy Karch) 568
A) Diarrhea
B) Urinary retention
C) Peripheral edema
D) Increased appetite
Ans: C
Feedback:
Peripheral edema is an identified adverse effect of leuprolide therapy. Constipation not diarrhea;
urinary frequency not urinary retention; and anorexia not increased appetite are also identified adverse
effects.
4. After administering somatropin (Saizen) to an 11-year-old patient with growth failure, what outcome
would indicate that the drug should be stopped?
A) Early sexual development
B) Thyroid overactivity
C) Closure of the epiphyses in long bones
D) Gynecomastia
Ans: C
Feedback:
Closure of the epiphyses is a sign that the drug should be stopped. Early sexual development, thyroid
overactivity, and gynecomastia would not be associated with this drug.
5. The nurse administers desmopressin (DDAVP) to the patient to treat diabetes insipidus. What
assessment finding would indicate to the nurse that the desmopressin is producing a therapeutic effect?
A) Decreased urine output
B) Decreased water reabsorption
C) Increased plasma osmolarity
Test Bank – Focus on Nursing Pharmacology (7th Edition by Amy Karch) 569
D) Decreased blood volume
Ans: A
Feedback:
Desmopressin produces its antidiuretic activity in the kidneys, causing the cortical and medullary parts
of the collecting duct to become permeable to water, thereby increasing water reabsorption and
decreasing urine formation. These activities reduce plasma osmolarity and increase blood volume.