Pharmacology And the Nursing Process 8e by Linda Lane-Collins -Julie S. Snyder
Pharmacology And the Nursing Process 8e by Linda Lane-Collins -Julie S. Snyder
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Chapter 42: Antifungal Drugs
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | Discontinue the infusion immediately. |
| b. | Reduce the infusion rate gradually until the adverse effects subside. |
| c. | Administer the medication by rapid IV infusion to reduce these effects. |
| d. | Nothing; these are expected side effects of this medication. |
ANS: A
Once the intravenous infusion of amphotericin B has begun, vital signs must be monitored frequently to assess for adverse reactions such as cardiac dysrhythmias, visual disturbances, paresthesias (numbness or tingling of the hands or feet), respiratory difficulty, pain, fever, chills, and nausea. If these adverse effects or a severe reaction occur, the infusion must be discontinued (while the patient is closely monitored) and the prescriber contacted. The other options are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 676
TOP: NURSING PROCESS: Implementation
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | Reduced action of oral anticoagulants |
| b. | Increased effects of oral anticoagulants |
| c. | Hypokalemia |
| d. | Decreased effectiveness of the antifungal drug |
ANS: B
Azole antifungal drugs increase the effects of oral anticoagulants. As a result, increased bleeding may occur. The other options are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 675
TOP: NURSING PROCESS: Assessment
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | Discontinuing the infusion immediately if fever, chills, or nausea occur |
| b. | Gradually increasing the infusion rate until the expected adverse effects occur |
| c. | If fever, chills, or nausea occur during the infusion, administering medications to treat the symptoms |
| d. | Before beginning the infusion, administering an antipyretic and an antiemetic drug |
ANS: D
Almost all patients given the drug intravenously experience fever, chills, hypotension, tachycardia, malaise, muscle and joint pain, anorexia, nausea and vomiting, and headache. For this reason, pretreatment with an antipyretic (acetaminophen), antihistamines, and antiemetics may be conducted to decrease the severity of the infusion-related reaction. The other options are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 672
TOP: NURSING PROCESS: Implementation
MSC: NCLEX: Physiological Integrity: Reduction of Risk Potential
| a. | The lipid formulations may be given in oral form. |
| b. | The doses are much lower than the doses of the older drugs. |
| c. | The lipid formulations are associated with fewer adverse effects than the older drugs. |
| d. | There is no difference in cost between the newer and older forms. |
ANS: C
Newer lipid formulations of amphotericin B have been developed in an attempt to decrease the incidence of its adverse effects and increase its efficacy. However, the lipid formulations are more costly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: p. 673
TOP: NURSING PROCESS: Implementation
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapie
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