Chapter 44: Drugs Used to Treat the Musculoskeletal System

Basic Pharmacology For Nurses 17Th Ed By Clayton

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Chapter 44: Drugs Used to Treat the Musculoskeletal System

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. A patient who has undergone a lengthy surgical procedure under general anesthesia is unable to breathe on his own following the procedure. Which drug will the nurse expect to be administered as an antidote to the neuromuscular-blocking agent?
a. Dantrolene (Dantrium)
b. Neostigmine methylsulfate (Prostigmin)
c. Ether
d. Baclofen (Lioresal)

 

 

ANS:  B

Neostigmine methylsulfate is an antidote to neuromuscular-blocking agents. Additional measures to implement include artificial respirations with oxygen and atropine sulfate for bradycardia and hypotension. Dantrolene is a direct-acting skeletal muscle relaxant given for the treatment of neuroleptic malignant syndrome associated with the use of antipsychotic agents. Ether is a general anesthetic. Baclofen is a skeletal muscle relaxant.

 

DIF:    Cognitive Level: Application           REF:   Page 684        OBJ:   4

TOP:   Nursing Process Step: Implementation

MSC:  NCLEX Client Needs Category: Physiological Integrity

NOT:  CONCEPT(S): Clinical Judgment; Safety; Gas Exchange

 

  1. What is the reason for a paraplegic patient to receive baclofen (Lioresal)?
a. It interrupts reflexes at the level of the spinal cord.
b. It acts directly on the skeletal muscles to reduce spasticity.
c. It interrupts transmission of impulses from motor nerves to muscles at the skeletal neuromuscular junction.
d. It produces generalized mild weakness of skeletal muscles and decreases the force of reflex muscle contractions.

 

 

ANS:  A

Baclofen is a gamma aminobutyric acid derivative that interrupts polysynaptic reflexes at the level of the spinal cord. Baclofen does not appear to act directly on the skeletal muscles. Interrupting transmission of impulses from motor nerves to muscles at the skeletal neuromuscular junction is the mechanism of action of neuromuscular-blocking agents. Producing generalized mild weakness of skeletal muscles and decreasing the force of reflex muscle contractions is the mechanism of action of dantrolene.

 

DIF:    Cognitive Level: Comprehension     REF:   Page 682        OBJ:   2 | 3

TOP:   Nursing Process Step: Implementation

MSC:  NCLEX Client Needs Category: Physiological Integrity

NOT:  CONCEPT(S): Clinical Judgment

 

  1. A patient taking antipsychotic medication for schizophrenia is admitted with a temperature of 106° F. The admitting diagnosis is neuroleptic malignant syndrome resulting from antipsychotic medication. Which drug is indicated in treatment of this condition?
a. Edrophonium (Tensilon)
b. Dantrolene (Dantrium)
c. Baclofen (Lioresal)
d. Metaxalone (Skelaxin)

 

 

ANS:  B

Dantrolene, a direct-acting skeletal muscle relaxant, is used to treat neuroleptic malignant syndrome associated with the use of antipsychotic agents. Edrophonium is an antidote for neuromuscular-blocking agents. Baclofen is a skeletal muscle relaxant used for the treatment of muscle spasticity resulting from multiple sclerosis (MS) and cerebral palsy. Metaxalone is used for muscle spasms.

 

DIF:    Cognitive Level: Comprehension     REF:   Page 683        OBJ:   2 | 3

TOP:   Nursing Process Step: Implementation

MSC:  NCLEX Client Needs Category: Physiological Integrity

NOT:  CONCEPT(S): Clinical Judgment; Safety

 

  1. In the intensive care unit, the nurse is taking care of a patient who is on a ventilator and is receiving succinylcholine (Anectine). Which is a priority nursing diagnosis for this patient?
a. Pain
b. Disturbed body image
c. Risk for injury
d. Self-care deficit

 

 

ANS:  A

Pain is the highest priority, according to Maslow’s hierarchy of needs. Succinylcholine, a neuromuscular-blocking agent, is used to paralyze muscles while a patient is on a ventilator. Neuromuscular-blocking agents do not relieve pain. Disturbed body image is not a priority for this situation, although it does apply. Risk for injury and self-care deficit are not as great of priorities for this situation.

 

DIF:    Cognitive Level: Application           REF:   Page 684 | Page 685

OBJ:   1 | 4                TOP:   Nursing Process Step: Diagnosis

MSC:  NCLEX Client Needs Category: Physiological Integrity

NOT:   CONCEPT(S): Clinical Judgment; Pain

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