Chapter 45: Antipsychotic drugs

Chapter 45: Antipsychotic drugs

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. The glutamate hypothesis of schizophrenia is based in part on the

1. increased glutamate receptor densities found in schizophrenic brains
2. decreased glutamate receptor densities found in schizophrenic brains
3. reduction of schizophrenic symptoms by glutamate antagonists
4. reduction of schizophrenic symptoms by glutamate agonists
5. occurrence of psychotic symptoms in persons given glutamate agonists

Answer b: decreased glutamate receptor densities found in schizophrenic brains

1. Because of the risk of agranulocytosis, periodic blood counts are required in persons receiving

1. haloperidol
2. quetiapine
3. risperidone
4. clozapine
5. sulpiride

Answer d: clozapine

1. The dopamine hypothesis of schizophrenia is primarily supported by the

1. decreased dopamine synthesis found in schizophrenic patients
2. increased excretion of dopamine metabolites in schizophrenic patients
3. increased dopamine D₂ receptor density found in schizophrenic patients
4. decreased dopamine D₂ receptor density found in schizophrenic patients
5. correlation between dopamine D₂ receptor binding and clinical potency of antipsychotic drugs

Answer e: correlation between dopamine D₂ receptor binding and clinical potency of antipsychotic drugs

1. The primary endocrine effect of most antipsychotic drugs is

1. increased secretion of prolactin
2. decreased secretion of prolactin
3. increased secretion of growth hormone
4. decreased secretion of growth hormone
5. increased secretion of thyrotropin

Answer a: increased secretion of prolactin