Chapter 47: Biologic Response–Modifying and Antirheumatic Drugs

Chapter 47: Biologic Response–Modifying and Antirheumatic Drugs

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

1. When monitoring a patient’s response to interferon therapy, the nurse notes that the major dose-limiting factor for interferon therapy is which condition?

a.	Diarrhea
b.	Fatigue
c.	Anxiety
d.	Nausea and vomiting

 

 

ANS:  B

Patients who receive interferon therapy may experience flu-like symptoms: fever, chills, headache, malaise, myalgia, and fatigue. Fatigue is the major dose-limiting factor for interferon therapy. Patients taking high dosages become so exhausted that they are commonly confined to bed.

 

DIF:    COGNITIVE LEVEL: Understanding (Comprehension)    REF:   p. 754

TOP:   NURSING PROCESS: Evaluation

MSC:  NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

 

2. A patient asks about his cancer treatment with monoclonal antibodies. The nurse tells him that which is the major advantage of treating certain cancers with monoclonal antibodies?

a.	They will help the patient improve more quickly than will other antineoplastic drugs.
b.	They are more effective against metastatic tumors.
c.	Monoclonal antibodies target certain tumor cells and bypass normal cells.
d.	There are fewer incidences of opportunistic infections with monoclonal antibodies.

 

 

ANS:  C

Monoclonal antibodies can target cancer cells specifically and have minimal effects on healthy cells, unlike conventional cancer treatments. As a result, there are fewer adverse effects when compared to traditional antineoplastic therapy. The other options are incorrect.

 

DIF:    COGNITIVE LEVEL: Understanding (Comprehension)    REF:   p. 755

TOP:   NURSING PROCESS: Planning

MSC:  NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

 

3. During a patient’s therapy with interleukins, the nurse monitors the patient for capillary leak syndrome. Which assessment finding, if present, would indicate this problem?

a.	Bradycardia
b.	A dry cough
c.	Bruising on the skin
d.	A sudden, 15-pound weight gain

 

 

ANS:  D

With capillary leak syndrome, the capillaries lose their ability to retain vital colloids, and these substances migrate into the surrounding tissues, resulting in massive fluid retention. As a result, heart failure, myocardial infarction, and dysrhythmias may occur. The other options do not reflect capillary leak syndrome.

 

DIF:    COGNITIVE LEVEL: Applying (Application)                  REF:   p. 760

TOP:   NURSING PROCESS: Assessment

MSC:  NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

 

4. A patient who has received chemotherapy has a critically low platelet count. The nurse expects which drug or drug class to be used to stimulate platelet cell production?

a.	Filgrastim (Neupogen)
b.	Interferons
c.	Oprelvekin (Neumega)
d.	Epoetin alfa (Epogen)

 

 

ANS:  C

Oprelvekin (Neumega) stimulates bone marrow cells, specifically megakaryocytes, which eventually form platelets. The other options are incorrect.

 

DIF:    COGNITIVE LEVEL: Applying (Application)                  REF:   p. 753

TOP:   NURSING PROCESS: Planning

MSC:  NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies