Pathophysiology, 5th Edition By Lee-Ellen C. Copstead
Pathophysiology, 5th Edition By Lee-Ellen C. Copstead
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Chapter 48: Neurobiology of Psychotic Illnesses
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | generalized anxiety. |
| b. | depression. |
| c. | disorganized thinking. |
| d. | eating disorders. |
ANS: C
Schizophrenia is now correctly understood as a split or separation among normally well-synchronized brain functions. This loss of synchronized brain functioning leads to thoughts, behaviors, and feelings that are disordered, disorganized, and disconnected from reality. Generalized anxiety and eating disorders are not associated with schizophrenia. Schizophrenia is not characterized by depression.
REF: Pg. 975
| a. | before puberty. |
| b. | 15 to 25 years. |
| c. | 40 to 65 years. |
| d. | after 65 years. |
ANS: B
The most common age of onset and diagnosis is between 15 and 25 years for men. Women are typically diagnosed between 25 and 35 years. Most persons first diagnosed with schizophrenia are between the ages of 15 and 54 years. The usual age of onset of schizophrenia occurs before the age of 25.
REF: Pg. 975
| a. | Social withdrawal |
| b. | Flat affect |
| c. | Lack of speech |
| d. | Hallucinations |
ANS: D
Positive symptoms include the psychotic dimension, or distortions in thought content (delusions) and perception (hallucinations), as well as the disorganization dimension, or disorganization in speech and behavior. Asociality is considered a negative symptom. Flat affect is considered to be a cognitive symptom. Lack of speech is not considered to be a positive symptom of schizophrenia.
REF: Pg. 978
| a. | are more easily managed than the positive symptoms. |
| b. | are thought to be mediated by D1 receptors in the brain. |
| c. | include rambling speech and delusional thoughts. |
| d. | are due to a deficiency of brain dopamine. |
ANS: B
Negative symptoms of schizophrenia are thought to be associated with dopamine D1 receptor activity in the brain. Negative symptoms can be more difficult to recognize than positive symptoms. Rambling speech and delusional thoughts are positive symptoms. The positive symptoms of schizophrenia are thought to result from excessive dopamine D2 receptor activity in the brain.
REF: Pg. 978
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