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Chapter 49: Miscellaneous Agents

Basic Pharmacology For Nurses 17Th Ed By Clayton

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Chapter 49: Miscellaneous Agents

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. The nurse is caring for a patient diagnosed with gout who has elevated uric acid levels. Which medication will likely be administered?
a. Allopurinol (Zyloprim)
b. Disulfiram (Antabuse)
c. Lactulose (Cephulac)
d. Memantine (Namenda)

 

 

ANS:  A

Allopurinol blocks the terminal step in uric acid formation by inhibiting the enzyme xanthine oxidase. Disulfiram, lactulose, and memantine do not lower uric acid levels.

 

DIF:    Cognitive Level: Knowledge            REF:   Page 797        OBJ:   1

TOP:   Nursing Process Step: Assessment

MSC:  NCLEX Client Needs Category: Physiological Integrity

NOT:  CONCEPT(S): Clinical Judgment

 

  1. The nurse is providing information to a patient with chronic gout arthritis who is prescribed probenecid. Which information by the nurse is accurate regarding the action of this drug?
a. It prevents uric acid crystal formation.
b. It promotes uric acid excretion.
c. It provides analgesia.
d. It treats acute gout attacks.

 

 

ANS:  B

Probenecid promotes renal excretion of uric acid and inhibits the reabsorption of urate in the kidney, which results in the reduction of uric acid in the blood. It is used to treat hyperuricemia and chronic gouty arthritis. The primary therapeutic outcome expected with probenecid therapy is prevention of acute attacks of gouty arthritis. Probenecid does not prevent formation of uric acid crystals or provide analgesia. Colchicines provide relief from acute attacks of gout.

 

DIF:    Cognitive Level: Comprehension     REF:   Page 796        OBJ:   1 | 2

TOP:   Nursing Process Step: Implementation

MSC:  NCLEX Client Needs Category: Psychosocial Integrity

NOT:  CONCEPT(S): Clinical Judgment; Patient Education

 

  1. The nurse receives an order to administer colchicine 0.6 mg every 1 to 2 hours until the patient exhibits adverse effects. The nurse will monitor for which adverse effect?
a. Diminished fever
b. Diarrhea or nausea
c. Increased urination
d. Decrease in erythema

 

 

ANS:  B

During an acute attack, initially 0.5 to 1.3 mg of colchicine are administered, followed by 0.6 mg every 1 to 2 hours until pain subsides, or nausea, vomiting, and diarrhea develop. Fever is not associated with gout, and colchicine does not reduce fever. Colchicine does not increase urinary output or frequency or affect erythema.

 

DIF:    Cognitive Level: Comprehension     REF:   Page 794        OBJ:   1

TOP:   Nursing Process Step: Assessment

MSC:  NCLEX Client Needs Category: Psychosocial Integrity

NOT:  CONCEPT(S): Clinical Judgment; Safety

 

  1. Which laboratory test result would the nurse observe when a patient has hepatotoxicity?
a. Decreased bilirubin
b. Increased albumin
c. Decreased alkaline phosphatase
d. Increased alanine aminotransferase (ALT)

 

 

ANS:  D

The symptoms of hepatotoxicity are anorexia, nausea, vomiting, jaundice, hepatomegaly, splenomegaly, and abnormal liver function test results (elevated bilirubin, aspartate aminotransferase [AST], ALT, gamma-glutamyl transpeptidase [GGT], alkaline phosphatase, prothrombin time). Bilirubin increases with hepatotoxicity. Albumin decreases with hepatotoxicity. Alkaline phosphatase increases with hepatotoxicity.

 

DIF:    Cognitive Level: Application           REF:   Page 798        OBJ:   1

TOP:   Nursing Process Step: Evaluation

MSC:  NCLEX Client Needs Category: Psychosocial Integrity

NOT:  CONCEPT(S): Clinical Judgment

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