Basic Pharmacology For Nurses,15th Edition by Bruce D. Clayton
Basic Pharmacology For Nurses,15th Edition by Bruce D. Clayton
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Chapter 50: Miscellaneous Agents
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| A. | Allopurinol (Zyloprim) |
| B. | Disulfiram (Antabuse) |
| C. | Lactulose (Cephulac) |
| D. | Memantine (Namenda) |
ANS: A
| Feedback | |
| A | Allopurinol blocks the terminal step in uric acid formation by inhibiting the enzyme xanthine oxidase. |
| B | Disulfiram does not lower uric acid levels. |
| C | Lactulose does not lower uric acid levels. |
| D | Memantine does not lower uric acid levels. |
DIF: Cognitive Level: Knowledge REF: 843
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity
| A. | To increase daily urine output |
| B. | To relieve constipation |
| C. | To reduce formation of ammonia in the gut |
| D. | To maintain electrolyte values within normal limits |
ANS: C
| Feedback | |
| A | Lactulose does not increase urine output. |
| B | Lactulose is a laxative, but that is not why it is given in end-stage liver disease. |
| C | Symptoms associated with end-stage liver disease are portal hypertension and ascites and/or accumulation of fluid in the abdominal cavity. Elevated ammonia levels contribute to encephalopathy associated with chronic alcoholism. Lactulose is prescribed to reduce formation of ammonia in the gut. |
| D | Lactulose does not maintain normal electrolyte balance. |
DIF: Cognitive Level: Application REF: 847
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Psychosocial Integrity
| A. | It prevents uric acid crystal formation. |
| B. | It promotes uric acid excretion. |
| C. | It provides analgesia. |
| D. | It treats acute gout attacks. |
ANS: B
| Feedback | |
| A | Probenecid does not prevent formation of uric acid crystals. |
| B | Probenecid promotes renal excretion of uric acid and inhibits the reabsorption of urate in the kidney, which results in the reduction of uric acid in the blood. It is used to treat hyperuricemia and chronic gouty arthritis. The primary therapeutic outcome expected with probenecid therapy is prevention of acute attacks of gouty arthritis. |
| C | Probenecid does not provide analgesia. |
| D | Colchicines provide relief from acute attacks of gout. |
DIF: Cognitive Level: Comprehension REF: 848
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Psychosocial Integrity
| A. | Diminished fever |
| B. | Diarrhea or nausea |
| C. | Increased urination |
| D. | Decrease in erythema |
ANS: B
| Feedback | |
| A | Fever is not associated with gout, and colchicine does not reduce fever. |
| B | During an acute attack, initially 0.5 to 1.3 mg are administered, followed by 0.6 mg every 1 to 2 hours until pain subsides, or nausea, vomiting, and diarrhea develop. |
| C | Colchicine does not increase urinary output or frequency. |
| D | Colchicine does not affect erythema. |
DIF: Cognitive Level: Comprehension REF: 844
TOP: Nursing Process Step: Assessment
MSC: NCLEX Client Needs Category: Psychosocial Integrity
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