Chapter 50: Miscellaneous Agents

Chapter 50: Miscellaneous Agents

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. The nurse is caring for a patient diagnosed with gout who has elevated uric acid levels. Which medication will likely be administered?

ANS:  A

Allopurinol blocks the terminal step in uric acid formation by inhibiting the enzyme xanthine oxidase. Disulfiram, lactulose, and memantine do not lower uric acid levels.

DIF:    Cognitive Level: Knowledge            REF:   p. 855             OBJ:   1

TOP:   Nursing Process Step: Assessment

MSC:  NCLEX Client Needs Category: Physiological Integrity

2. The nurse is providing information to a patient with chronic gout arthritis who is prescribed probenecid. Which information by the nurse is accurate regarding the action of this drug?

ANS:  B

Probenecid promotes renal excretion of uric acid and inhibits the reabsorption of urate in the kidney, which results in the reduction of uric acid in the blood. It is used to treat hyperuricemia and chronic gouty arthritis. The primary therapeutic outcome expected with probenecid therapy is prevention of acute attacks of gouty arthritis. Probenecid does not prevent formation of uric acid crystals or provide analgesia. Colchicines provide relief from acute attacks of gout.

DIF:    Cognitive Level: Comprehension     REF:   p. 853             OBJ:   1 | 2

TOP:   Nursing Process Step: Implementation

MSC:  NCLEX Client Needs Category: Psychosocial Integrity

3. The nurse receives an order to administer colchicine 0.6 mg every 1 to 2 hours until the patient exhibits adverse effects. The nurse will monitor for which adverse effect?

ANS:  B

During an acute attack, initially 0.5 to 1.3 mg of colchicine are administered, followed by 0.6 mg every 1 to 2 hours until pain subsides, or nausea, vomiting, and diarrhea develop. Fever is not associated with gout, and colchicine does not reduce fever. Colchicine does not increase urinary output or frequency or affect erythema.

DIF:    Cognitive Level: Comprehension     REF:   p. 851             OBJ:   1

TOP:   Nursing Process Step: Assessment

MSC:  NCLEX Client Needs Category: Psychosocial Integrity

4. Which laboratory test result would the nurse observe when a patient has hepatotoxicity?

ANS:  D

The symptoms of hepatotoxicity are anorexia, nausea, vomiting, jaundice, hepatomegaly, splenomegaly, and abnormal liver function test results (elevated bilirubin, aspartate aminotransferase [AST], ALT, gamma glutamyl transpeptidase [GGT], alkaline phosphatase, prothrombin time). Bilirubin increases with hepatotoxicity. Albumin decreases with hepatotoxicity. Alkaline phosphatase increases with hepatotoxicity.

DIF:    Cognitive Level: Application           REF:   p. 856             OBJ:   1

TOP:   Nursing Process Step: Evaluation

MSC:  NCLEX Client Needs Category: Psychosocial Integrity