Chapter 51: Antiviral drugs

Chapter 51: Antiviral drugs

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. Which reverse transcriptase inhibitor achieves the highest percentage of plasma drug concentrations in the cerebrospinal fluid?

1. lamivudine
2. abacavir
3. stavudine
4. zidovudine
5. efavirenz

Answer d: zidovudine

1. The mortality due to Lassa fever is significantly reduced in persons treated with

1. tribavirin (ribavirin)
2. foscarnet
3. ganciclovir
4. interferon alpha
5. oseltamivir

Answer a: tribavirin (ribavirin)

1. Efavirenz inhibits human immunodeficiency virus reverse transcriptase by

1. competing with nucleotides for the active site of the enzyme
2. binding near the catalytic site and denaturing it
3. incorporation into nascent DNA, causing chain termination
4. inhibiting formation of nucleotide triphosphates
5. inhibiting maturation of viral polyproteins

Answer b: binding near the catalytic site and denaturing it

1. The preferred drug for treating active infections of cytomegalovirus is

1. acyclovir
2. foscarnet
3. lamivudine
4. nevirapine
5. ganciclovir

Answer e: ganciclovir