Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne
Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne
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Chapter 52: Management of ST-Elevation Myocardial Infarction
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
| a. | Meperidine (Demerol) |
| b. | Morphine |
| c. | Aspirin |
| d. | Hydromorphone (Dilaudid) |
ANS: B
Morphine is the treatment of choice for STEMI-associated pain. Morphine can also improve hemodynamics through its combined effects on preload and afterload. As a result, cardiac oxygen demand is reduced, which helps preserve ischemic myocardium.
Meperidine and hydromorphone are not indicated for relief of cardiac chest pain.
Although aspirin substantially reduces mortality, it is not indicated for pain relief but rather for its ability to suppress platelet aggregation.
DIF: Cognitive Level: Application REF: p. 621
TOP: Nursing Process: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | reperfusion therapy. |
| b. | morphine. |
| c. | nitroglycerin. |
| d. | aspirin. |
ANS: A
Reperfusion therapy, which includes fibrinolytic therapy or primary percutaneous coronary intervention (PCI), is the most effective way to preserve myocardial function and limit infarct size.
Morphine is indicated for the treatment of cardiac pain. In addition, through combined reduction of preload and afterload, morphine reduces oxygen demand, which helps preserve ischemic myocardium. However, morphine alone is not the most effective way to limit the size of a myocardial infarction.
Nitroglycerin reduces preload, thereby reducing oxygen demand. It also increases collateral blood flow to ischemic regions of the heart, which helps limit infarct size. However, nitroglycerin alone is not the most effective way to limit the size of a myocardial infarction and has not been shown to reduce mortality.
Aspirin is indicated to suppress platelet aggregation. Research has demonstrated a reduction in mortality when aspirin is administered to patients with an evolving STEMI. However, aspirin alone is not the most effective way to limit the size of a myocardial infarction.
DIF: Cognitive Level: Application REF: p. 621
TOP: Nursing Process: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity: Reduction of Risk Potential
| a. | The patient just completed her last menstrual cycle. |
| b. | The patient states that the chest pain started 1 hour ago. |
| c. | The patient has a history of a small cerebral aneurysm. |
| d. | The patient has hypertension that is well controlled by diuretic therapy. |
ANS: C
The absolute contraindications to thrombolytic therapy include known structural cerebrovascular lesions. This patient has a known cerebral aneurysm.
Active internal bleeding is an absolute contraindication for thrombolysis except for menses, and the patient has indicated she has completed her last cycle. There is no contraindication to administration.
Current guidelines indicate that thrombolytic therapy should be administered for chest pain that has been present for no longer than 12 hours. The patient meets this criterion for administration.
Although severe, poorly controlled hypertension is a relative contraindication, the patient’s hypertension is well controlled by medication therapy. Thrombolytics can be administered with caution.
DIF: Cognitive Level: Analysis REF: p. 622
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | Cardiac troponin T |
| b. | Potassium level |
| c. | Creatine kinase (CK) |
| d. | B-type natriuretic peptide (BNP) |
ANS: A
Cardiac-derived troponins (T and I) are considered the best serum markers for suspected STEMI. Cardiac troponins are detectable within 2 to 4 hours after symptom onset if infarction has occurred.
Measurement of the potassium level is not indicated. However, it should be evaluated in ST depression, which can be the result of hypokalemia or hyperkalemia.
A CK level is not specific enough. Unless specific isoenzymes are evaluated, it is not clear whether elevations are the result of other problems, such as musculoskeletal, cerebral, or renal injury.
BNP is used to diagnose heart failure.
DIF: Cognitive Level: Application REF: p. 620
TOP: Nursing Process: Planning
MSC: NCLEX Client Needs Category: Physiological Integrity: Reduction of Risk Potential
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