Chapter 55: Anticancer drugs

Chapter 55: Anticancer drugs

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. A cytoplasmic kinase (Bcr/Abl) involved in the pathogenesis of chronic myeloid leukemia is inhibited by

1. crisantaspase
2. anastrozole
3. imatinib
4. rituximab
5. aldesleukin

Answer c: imatinib

1. Cumulative dose-related cardiac toxicity typically results from administration of

1. doxorubicin
2. bleomycin
3. vincristine
4. imatinib
5. irinotecan

Answer a: doxorubicin

1. Goserelin is used in treating advanced prostate cancer because of its ability to

1. increase gonadotrophin secretion
2. reduce gonadotrophin secretion
3. block testosterone receptors
4. activate estrogen receptors
5. inhibit estrogen synthesis

Answer b: reduce gonadotrophin secretion

1. Vincristine inhibits mitosis of cancer cells at metaphase by

1. inhibiting telomerase
2. increasing tubulin degradation
3. inhibiting synthesis of tubulin
4. inhibiting polymerization of tubulin
5. stabilizing microtubules

Answer d: inhibiting polymerization of tubulin