Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew
Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew
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Chapter 56: Drugs for Breast Cancer
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | vitamin E is not harmful but has not been shown to change outcomes. |
| b. | no supplements have been shown to alter outcomes or response to therapy. |
| c. | folic acid and other B vitamins may improve ability to tolerate chemotherapy. |
| d. | vitamin C, taken at least 6 days per week, may lower her risk of cancer recurrence. |
ANS: D
Women with early-stage breast cancer who took supplements of vitamin C or vitamin E at least 6 days per week had a lower risk of cancer recurrence with vitamin C but no differences with vitamin E. B vitamins are not listed as effective.
DIF: Cognitive Level: Understanding (Comprehension) REF: 647
| a. | toremifene (Fareston). |
| b. | tamoxifen (Nolvadex). |
| c. | fulvestrant (Faslodex). |
| d. | anastrozole (Arimidex). |
ANS: D
Anastrozole (Arimidex) is a selective aromatase inhibitor and is useful in postmenopausal women who have estrogen receptor–negative breast cancer. The other medications are antiestrogens and treat estrogen receptor–positive cancer.
DIF: Cognitive Level: Applying (Application) REF: 648
| a. | a chest radiograph. |
| b. | bone mineral density testing. |
| c. | serum bilirubin and creatinine. |
| d. | liver enzymes and a complete blood count (CBC). |
ANS: D
Patients taking antiestrogens, such as tamoxifen, should have periodic monitoring of liver enzymes and a CBC. A chest radiograph is not indicated. Bilirubin, creatinine, and bone mineral density testing are part of routine testing for patients taking aromatase inhibitors.
DIF: Cognitive Level: Applying (Application) REF: 648
| a. | schedule her for a gynecologic examination. |
| b. | recommend that she use a barrier method of contraception. |
| c. | tell her to stop taking the medication and call her oncologist. |
| d. | reassure her that these are normal side effects of the medication. |
ANS: A
Any abnormal vaginal discharge should be reported immediately and should be evaluated with a gynecologic examination to rule out carcinoma. She is not showing signs of ovulation, so contraception is not necessary. She should not stop taking the medication unless the gynecologic examination is positive. These are common side effects but are not always normal.
DIF: Cognitive Level: Applying (Application) REF: 648
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