Lehne's Pharmacology for Nursing Care 9th Edition by Jacqueline Burchum
Lehne's Pharmacology for Nursing Care 9th Edition by Jacqueline Burchum
$2.99
Chapter 56: Hematopoietic Agents
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | “Damage to the renal tubules increases serum blood loss.” |
| b. | “Dialysis accelerates the breakdown of red blood cells.” |
| c. | “Erythropoietin is no longer produced by cells in the kidneys.” |
| d. | “Patients with CRF are deficient in iron, folic acid, and vitamin B12.” |
ANS: C
Erythropoietin is normally produced by peritubular cells in the proximal tubules of the kidneys, but it is not produced in patients with CRF. Erythropoietin stimulates red blood cell (RBC) production; therefore, when it is absent, RBC production is compromised. Blood loss in damaged renal tubules does not cause low blood counts in patients with CRF. Dialysis does not contribute to low blood counts. Patients with CRF are not more likely to be deficient in iron, folic acid, and vitamin B12.
PTS: 1 DIF: Cognitive Level: Comprehension REF: p. 656
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
| a. | “If I have to start dialysis, I will have to stop taking this drug.” |
| b. | “Taking this drug will not eliminate my need for blood transfusions.” |
| c. | “Taking this medication will prevent the need for dialysis in the future.” |
| d. | “When I take this, my serum ferritin levels will increase.” |
ANS: B
Epoetin alfa virtually reduces, but does not eliminate, the need for blood transfusions in patients with CRF. Dialysis is not a contraindication for taking this drug. Epoetin alfa does not prevent the need for dialysis. Epoetin alfa does not raise the serum ferritin level.
PTS: 1 DIF: Cognitive Level: Application REF: p. 656
TOP: Nursing Process: Planning
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
| a. | Epoetin alfa |
| b. | Filgrastim (granulocyte colony–stimulating factor) |
| c. | Oprelvekin (interleukin-11) |
| d. | Sargramostim (granulocyte-macrophage colony-stimulating factor) |
ANS: C
Oprelvekin causes the kidneys to retain sodium and water, which causes peripheral edema and expansion of plasma volume. Some patients experience dyspnea. Fluid retention is not an adverse effect of epoetin alfa, filgrastim, or sargramostim.
PTS: 1 DIF: Cognitive Level: Analysis REF: p. 661
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
| a. | Bone pain |
| b. | Fatigue |
| c. | Headache |
| d. | Hemorrhage |
ANS: A
Filgrastim causes bone pain in about 25% of patients. The pain is dose related and usually mild to moderate. Fatigue, bleeding, and headache are not common side effects of filgrastim.
PTS: 1 DIF: Cognitive Level: Application REF: p. 659
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
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