Lehne's Pharmacology for Nursing Care 9th Edition by Jacqueline Burchum
Lehne's Pharmacology for Nursing Care 9th Edition by Jacqueline Burchum
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Chapter 61: Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
MULTIPLE CHOICE
| a. | an estrogen-progesterone product will reduce side effects. |
| b. | an intravaginal preparation may be best for her. |
| c. | side effects of ET are uncommon among women her age. |
| d. | transdermal preparations have fewer side effects. |
ANS: D
Transdermal preparations of estrogen have fewer adverse effects, use lower doses of estrogen, and have less fluctuation of estrogen levels than do oral preparations. Progesterone is contraindicated in women who have undergone hysterectomy. Intravaginal preparations are most useful for treating local estrogen deficiency such as vaginal and vulvar atrophy. Side effects of ET are the same at the patient’s age as for other women using ET.
PTS: 1 DIF: Cognitive Level: Application REF: p. 736
TOP: Nursing Process: Planning
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
| a. | Raloxifene reduces the risk of thromboembolism. |
| b. | The drug is associated with an increased risk of breast cancer. |
| c. | Use of this drug increases the risk of endometrial carcinoma. |
| d. | Vasomotor symptoms are a common side effect of this drug. |
ANS: D
Raloxifene can induce hot flashes in patients taking the drug. It increases the risk for thromboembolism. It protects against breast cancer and does not pose a risk of uterine cancer.
PTS: 1 DIF: Cognitive Level: Application REF: pp. 736-737
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
| a. | “Because I am not at risk for uterine cancer, I can take hormones indefinitely.” |
| b. | “I can take estrogen to reduce my risk of cardiovascular disease.” |
| c. | “I should take the lowest effective dose for the shortest time needed.” |
| d. | “I will need a progestin/estrogen combination since I have had a hysterectomy.” |
ANS: C
For patients who have undergone hysterectomy, progestin is unnecessary; estrogen-only preparations still carry increased risk of breast cancer and should be taken in the lowest effective dose for the shortest time possible. Even though uterine cancer is no longer a possibility, breast cancer is still a risk. Studies have shown no protection against coronary heart disease but increased risk of stroke and breast cancer with estrogens.
PTS: 1 DIF: Cognitive Level: Application REF: p. 741
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
| a. | “ET can provide protection against coronary heart disease and reverse osteoporosis.” |
| b. | “EPT is generally safer than ET, especially in women who have undergone hysterectomies.” |
| c. | “In women with established coronary heart disease, EPT can protect against myocardial infarction.” |
| d. | “Principle benefits of ET are suppression of menopausal symptoms and prevention of bone loss.” |
ANS: D
ET can be used to suppress menopausal symptoms and to prevent osteoporosis, but it carries risks of breast cancer and stroke, while conferring no preventive benefit for coronary heart disease. ET does not reverse osteoporosis but may help prevent it. EPT is not safer than ET; progestins appear to increase the risk of breast cancer. EPT does not prevent myocardial infarction in patients with coronary heart disease.
PTS: 1 DIF: Cognitive Level: Application REF: p. 741
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
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