Chapter 68: Antiretroviral Medications

Pharmacology For the Primary Care Provider 4th Edition by Edmunds Mayhew

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Chapter 68: Antiretroviral Medications

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. A female patient who is 8 weeks pregnant is seen by a primary care nurse practitioner (NP) after a routine prenatal screen was positive for human immunodeficiency virus (HIV). A CD4 cell count is 750 cells/mm. The NP should:
a. begin immediate therapy with zidovudine and lamivudine.
b. begin therapy with zidovudine when she is in her second trimester.
c. delay treatment with antiretroviral medications until after her pregnancy.
d. initiate therapy with zidovudine if her CD4 cell count decreases to 500 cells/mm.

 

 

ANS:  B

Patients who are HIV positive and who are pregnant should be treated with antiretroviral medications, but treatment should be avoided during the first trimester if possible. Zidovudine is recommended and has been shown to reduce the risk of transmission to the fetus from 25% to 8%.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   732

 

  1. A patient who has HIV has been receiving a two-drug combination therapy for 6 months. At an annual physical examination, the primary care NP notes that the patient has a viral load of 60 copies/mL and a CD4 cell count of 350 cells/mm. The NP should contact the patient’s infectious disease specialist to discuss:
a. changing one of the medications.
b. changing both of the medications.
c. increasing the dose of both medications.
d. discontinuing the medications for a short period.

 

 

ANS:  B

This patient has a high viral load and a low cell count. When changing medications, both medications should be changed.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   730

 

  1. A primary care NP provides primary care for a woman who has HIV. The woman asks the NP if she will ever be able to have children. The NP should tell her:
a. none of the antiretroviral medications are safe to take during pregnancy.
b. she will need to take medications throughout her pregnancy and lactation.
c. there is no risk of disease transmission to a fetus if she complies with therapy.
d. strict adherence to antiretroviral therapy decreases her risk of transmitting HIV to the fetus.

 

 

ANS:  D

Antiretroviral therapy reduces, but does not eliminate, the risk of transmitting HIV to the fetus. Antiretroviral therapy medications may be taken during pregnancy. Women with HIV should not breastfeed because of the high risk of transmission.

 

DIF:    Cognitive Level: Applying (Application)                           REF:   732

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